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Effects of Novel Probiotics in a Murine Model of Irritable Bowel Syndrome

Chung HG, Min YW, Lee C, Hong SN, Won JY, Jang JA, Kim CH, Chang DK

BACKGROUND/AIMS: Dysbiosis is an important factor in the pathogenesis of irritable bowel syndrome (IBS). Several studies have reported promising results using probiotics for the treatment of IBS. This study evaluated...
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Association between interstitial cells of Cajal and anti-vinculin antibody in human stomach

Kim JH, Nam SJ, Park SC, Lee SH, Kim TS, Lee M, Park JM, Choi DH, Kang CD, Lee SJ, Ryu YJ, Lee K, Park SY

Interstitial cells of Cajal (ICC) are known as the pacemaker cells of gastrointestinal tract, and it has been reported that acute gastroenteritis induces intestinal dysmotility through antibody to vinculin, a...
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Tobacco use, immunosuppressive, chronic pain, and psychiatric conditions are prevalent in women with symptomatic mesh complications undergoing mesh removal surgery

Blau EK, Adelstein , Amin KA, Durfy SJ, Lucioni A, Kobashi KC, Lee UJ

PURPOSE: To identify demographic and clinical characteristics of patients with symptomatic pelvic floor mesh complications who underwent mesh removal at our academic medical center. The secondary goal was to determine...
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Influencing Factors on Lactulose Breath Test Results

Kim JW, Park SY, Chung JO, Cho HA, Kim DH, Yoon JH, Park CH, Kim HS, Choi SK, Rew JS

BACKGROUND/AIMS: This study aimed to identify the demographic and clinical factors associated with positive breath-test results and to assess the relationship between hydrogen and methane production in patients with suspected...
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Non-celiac Gluten Sensitivity

Cha RR, Kim HJ

Non-celiac gluten sensitivity (NCGS) is a term that is used to describe individuals who are not affected by celiac disease or wheat allergy, yet they have intestinal and/or extra-intestinal symptoms...
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Is fecal calprotectin always normal in children with irritable bowel syndrome?

Choi YJ, Jeong SJ

BACKGROUND/AIMS: Fecal calprotectin (FC) is a marker of intraluminal intestinal inflammation. Intestinal inflammation may contribute to the pathophysiology of irritable bowel syndrome (IBS). This study evaluated FC levels in children...
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Importance of nutritional therapy in the management of intestinal diseases: beyond energy and nutrient supply

Kim SE

The gut is an immune-microbiome-epithelial complex. Gut microbiome-host interactions have widespread biological implications, and the role of this complex system extends beyond the digestion of food and nutrient absorption. Dietary...
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Obesity and Functional Gastrointestinal Disorders

Lee JY, Kwon JG, Kim SE, Diet, Obesity, and Metabolism Research Group of Korean Society of Neurogastroenterology and Motility

The prevalence of obesity and functional gastrointestinal disorders (FGIDs) is increasing worldwide. Obesity has been linked to gastroesophageal reflux disease, irritable bowel syndrome, functional dyspepsia, and various FGIDs. However, the...
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Tryptophan Metabolites in Irritable Bowel Syndrome: An Overnight Time-course Study

Burr RL, Gu H, Cain K, Djukovic D, Zhang X, Han C, Callan N, Raftery D, Heitkemper M

  • KMID: 2460485
  • J Neurogastroenterol Motil.
  • 2019 Oct;25(4):551-562.
  • doi: 10.5056/jnm19042
BACKGROUND/AIMS: Patients with irritable bowel syndrome (IBS) often report poor sleep quality. Whether poor sleep is associated with tryptophan (Trp) metabolites is unknown. We compared serum Trp metabolites in women...
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A Study of Irritable Bowel Syndrome and Stress on Female College Students in Korea

Shin J, Kim KJ, Bang JS

OBJECTIVE: The purpose of this study was to provide a database for making better decisions of the treatment of the irritable bowel syndrome (IBS) patient, and for improving the recognition...
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Prescription of Antibiotics for Adults with Acute Infectious Diarrhea in Korea: A Population-based Study

Lee HJ, Park KH, Park DA, Park J, Bang BW, Lee SS, Lee EJ, Kim YJ, Hong SK, Kim YR

BACKGROUND: Acute infectious diarrhea (AID) is a commonly observed condition globally. Several studies recommend against the use of empiric antibiotic therapy for AID, except in some cases of travelers' diarrhea....
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The role of fecal calprotectin in pediatric disease

Jeong SJ

Fecal calprotectin (FC) is a calcium- and zinc-binding protein of the S100 family, mainly expressed by neutrophils and released during inflammation. FC became an increasingly useful tool both for gastroenterologists...
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Evaluation of symptoms and symptom combinations in histamine intolerance

Schnedl WJ, Lackner S, Enko D, Schenk M, Holasek SJ, Mangge H

BACKGROUND/AIMS: Food intolerance/malabsorption, particularly histamine intolerance (HIT), may cause nonspecific functional gastrointestinal and extraintestinal symptoms. We evaluated gastrointestinal and extraintestinal symptoms in patients with HIT. METHODS: In an analysis of outpatients'...
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On Functional Connectivity and Symptom Relief After Gut-directed Hypnotherapy in Irritable Bowel Syndrome: A Preliminary Study

Simon RA, Engström , Icenhour A, Lowén M, Ström M, Tillisch K, Mayer E, Elsenbruch S, Walter S

  • KMID: 2454648
  • J Neurogastroenterol Motil.
  • 2019 Jul;25(3):478-479.
  • doi: 10.5056/jnm19069
No abstract available.
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Vagal Transient Receptor Potential Ankyrin 1 Mediates Stress-exacerbated Visceral Mechanonociception After Antral Cold Exposure

Chen X, Luo Q, Yan X, Li W, Chen S

  • KMID: 2454643
  • J Neurogastroenterol Motil.
  • 2019 Jul;25(3):442-460.
  • doi: 10.5056/jnm19014
BACKGROUND/AIMS: Abdominal pain can be evoked or exacerbated after gastrointestinal cold stimulation in some patients with diarrhea-predominant irritable bowel syndrome (IBS-D), indicating a low temperature-induced sensitization of visceral perception. We...
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Second Asian Consensus on Irritable Bowel Syndrome

Gwee KA, Gonlachanvit S, Ghoshal UC, Chua AS, Miwa H, Wu J, Bak YT, Lee OY, Lu CL, Park H, Chen M, Syam AF, Abraham P, Sollano J, Chang CS, Suzuki H, Fang X, Fukudo S, Choi MG, Hou X, Hongo M

  • KMID: 2454634
  • J Neurogastroenterol Motil.
  • 2019 Jul;25(3):343-362.
  • doi: 10.5056/jnm19041
BACKGROUND/AIMS: There has been major progress in our understanding of the irritable bowel syndrome (IBS), and novel treatment classes have emerged. The Rome IV guidelines were published in 2016 and...
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Depression Promotes the Onset of Irritable Bowel Syndrome through Unique Dysbiosis in Rats

Takajo T, Tomita K, Tsuchihashi H, Enomoto S, Tanichi M, Toda H, Okada Y, Furuhashi , Sugihara N, Wada A, Horiuchi K, Inaba K, Hanawa Y, Shibuya N, Shirakabe , Higashiyama M, Kurihara C, Watanabe C, Komoto S, Nagao S, Kimura K, Miura S, Shimizu K, Hokari R

BACKGROUND/AIMS: Although studies using conventional animal models have shown that specific stressors cause irritable bowel syndrome (IBS), it is unclear whether depression itself causes IBS. Our aim was to establish...
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Influence of Age and Body Mass Index on Total and Segmental Colonic Transit Times in Constipated Subjects

Bouchoucha M, Fysekidis , Rompteaux , Airinei G, Sabate JM, Benamouzig R

  • KMID: 2449098
  • J Neurogastroenterol Motil.
  • 2019 Apr;25(2):258-266.
  • doi: 10.5056/jnm18167
BACKGROUND/AIMS: Discordant data are found in the literature for the relationships between total and segmental colonic transit time (CTT) and demographic parameters. The aim of this study is to examine...
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Is Long-term Ambient Air Pollutant Exposure a Risk Factor for Irritable Bowel Syndrome in Children? A 12-year Longitudinal Cohort Study

Tan TK, Saps M, Lin CL, Wei CC

  • KMID: 2449096
  • J Neurogastroenterol Motil.
  • 2019 Apr;25(2):241-249.
  • doi: 10.5056/jnm18135
BACKGROUND/AIMS: Recent studies suggest that air pollution may play a role in gastrointestinal disorders. However, the effect of long-term exposure to air pollution on childhood irritable bowel syndrome (IBS) is...
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Psychosocial Factors Associated With Irritable Bowel Syndrome Development in Chinese College Freshmen

Jiang C, Xu Y, Sharma S, Zhang L, Wang H, Song J, Qian W, Bai T, Hou X

  • KMID: 2449095
  • J Neurogastroenterol Motil.
  • 2019 Apr;25(2):233-240.
  • doi: 10.5056/jnm18028
BACKGROUND/AIMS: The role of psychosocial factors on irritable bowel syndrome (IBS) in adolescents is incompletely understood. The aim of this study is to investigate the association between the psychosocial factors...
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