Korean J Gastroenterol.  2019 Mar;73(3):182-185. 10.4166/kjg.2019.73.3.182.

Pancreatic Metastasis from Adenocarcinoma of the Uterine Cervix

• Kim DJ
• Park JM
• Kim JH
• Nam K
• Kang CD
• Lee SJ
• Lee K
• Jeon YH

• KMID: 2442085
• DOI: http://doi.org/10.4166/kjg.2019.73.3.182

Abstract

Pancreatic metastasis from cervical cancer is extremely rare. We report a case of metastatic adenocarcinoma of the pancreas from uterine cervical cancer. A 70-year-old woman was referred because of a pancreatic mass detected by CT. She had been diagnosed with uterine cervical adenocarcinoma 20 months previously. After concurrent chemoradiotherapy, CT showed no evidence of the cervical mass, and follow-up showed no evidence of recurrence. Endoscopic ultrasound-guided fine needle aspiration biopsy of the pancreatic mass resulted in a diagnosis of metastatic adenocarcinoma from uterine cervix.

Keyword

Pancreas; Endoscopic ultrasound-guided fine needle aspiration; Adenocarcinoma; Uterine cervical neoplasms

MeSH Terms

Adenocarcinoma*
Aged
Biopsy
Cervix Uteri*
Chemoradiotherapy
Diagnosis
Endoscopic Ultrasound-Guided Fine Needle Aspiration
Female
Follow-Up Studies
Humans
Neoplasm Metastasis*
Pancreas
Recurrence
Uterine Cervical Neoplasms

Figure

• 

  Fig. 1 Abdominal computed tomography image showing a heterogeneously enhanced mass in the pancreatic body (white arrow).

• 

  Fig. 2 Magnetic resonance T2-weighted image showing a 3.5 cm mass in the pancreatic body (white dashed arrow).

• 

  Fig. 3 FDG PET/CT revealed abnormal FDG uptake in the pancreatic body (SUV max 5.9). FDG PET/CT, fluorodeoxyglucose positron emission tomography/computed tomography; SUV, standardized uptake value.

• 

  Fig. 4 Endoscopic ultrasound showed a hypoechoic mass in the pancreatic body; fine needle aspiration bioppsy was performed.

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  Fig. 5 Pathology of the pancreatic tumor showing atypical neoplastic glands with cellular crowding, stratification, and hyperchromatic nuclei (H&E, ×200).

• 

  Fig. 6 Tumor cells were positive for p16 by immunohistochemical staining (original magnification, ×200).

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