Mood Emot.  2018 Nov;16(3):134-139. 10.0000/me.2018.16.3.134.

Korean Medication Algorithm for Bipolar Disorder 2018 : Safety and Tolerability

Affiliations
  • 1Department of Psychiatry, Keyo Hospital, Keyo Medical Foundation, Uiwang, Korea.
  • 2Department of Psychiatry, College of Medicine, The Catholic University of Korea, Seoul, Korea. wmbahk@catholic.ac.kr
  • 3Department of Psychiatry, Naju National Hospital, Naju, Korea.
  • 4Department of Psychiatry, Sacred Heart Hospital, Hallym University, Anyang, Korea.
  • 5Department of Psychiatry, School of Medicine, Konkuk University, Chungju, Korea. sjs52632@hanmail.net
  • 6Department of Psychiatry, Seoul Paik Hospital, College of Medicine, Inje University, Seoul, Korea.
  • 7Department of Psychiatry, Haeundae Paik Hospital, College of Medicine, Inje University and Paik Institute for Clinical Research, Busan, Korea.
  • 8Department of Health Science and Technology, Graduate School of Inje University, Busan, Korea.
  • 9Department of Psychiatry, Jeju National University Hospital, Jeju, Korea.
  • 10Department of Psychiatry, Soonchunhyang University Cheonan Hospital, Soonchunhyang University, Cheonan, Korea.
  • 11Department of Psychiatry, Myongji Hospital, Goyang, Korea.
  • 12Department of Psychiatry, College of Medicine, Chung-Ang University, Seoul, Korea.

Abstract


OBJECTIVES
Treatment for bipolar disorder is often complicated by various clinical situations. We undertook a survey of expert opinions to facilitate clinical decisions in special situations such as weight gain, metabolic syndrome, hyperprolactinemia, genetic counseling, and treatment adherence.
METHODS
A written survey that asked treatment strategies related to safety and tolerability, was prepared focused on weight gain, antipsychotic related hyperprolactinemia, lamotrigine related skin rash, treatment non-adherence and genetic counseling. Sixty-one experts of the review committee completed the survey.
RESULTS
In the case of weight gain related to medications, experts preferred exercise and education for diet-control. First chosen medications were lamotrigine, aripiprazole and ziprasidone. Recommendations based on expert survey results for treatment of bipolar patients in other special situations are outlined.
CONCLUSION
With limitation of expert opinions, authors hope that results of this study provide valuable information to make clinical decisions about treatment of bipolar disorder in complicated situations.

Keyword

Bipolar disorder; Weight gain; Non-adherence; Lamotrigine; Hyperprolactinemia; Genetic counselling; Algorithm

MeSH Terms

Advisory Committees
Aripiprazole
Bipolar Disorder*
Education
Exanthema
Expert Testimony
Genetic Counseling
Hope
Humans
Hyperprolactinemia
Weight Gain
Aripiprazole
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