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Serum Prolactin and Bone Mineral Density in Schizophrenia: A Systematic Review

Lally J, Sahl AB, Murphy KC, Gaughran F, Stubbs B

The relationship between serum prolactin and bone mineral density (BMD) in schizophrenia is unclear. We conducted a literature review of databases from inception until December 2018 for cross-sectional, case-control, prospective...
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Macroprolactinoma in a young man presenting with erectile dysfunction

Song SH, Lee J, Kim DS

Hyperprolactinemia due to a pituitary adenoma is a rare cause of erectile dysfunction (ED). The prevalence of clinically apparent prolactinomas is reported to be from 6–10 to 50 per 100,000....
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Hyperprolactinemia after taking Levosulpiride and its Causality Assessment: An Adverse Event Reported by a Community Pharmacy

Lee H, Jo YJ, Yoon JS, Ji E

Levosulpiride is one of the most frequently prescribed medicines in Korea. An adverse drug reaction (ADR) after taking levosulpiride was reported at a community pharmacy in Korea. A 31-year-old woman...
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Korean Medication Algorithm for Bipolar Disorder 2018 : Safety and Tolerability

Sohn I, Bahk WM, Yoon BH, Jon DI, Seo JS, Kim W, Lee JG, Woo YS, Jeong JH, Kim MD, Jung YE, Shim SH, Song HR, Min KJ

OBJECTIVES: Treatment for bipolar disorder is often complicated by various clinical situations. We undertook a survey of expert opinions to facilitate clinical decisions in special situations such as weight gain,...
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Serum Prolactin Levels in Patients with Major Depressive Disorder Receiving Selective Serotonin-Reuptake Inhibitor Monotherapy for 3 Months: A Prospective Study

Park YM

OBJECTIVE: It is unclear whether selective serotonin-reuptake inhibitors (SSRIs) can significantly increase the prolactin level. The purpose of this study was to identify the relationship between the prolactin level and...
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The Relationship between the Amisulpride-Induced Hyperprolactinemia and Taq1A Polymorphism of the Dopamine D2 Receptor Gene in Schizophrenia Patients

Kim JJ, Seo MJ, Choi TY, Lee JH

OBJECTIVES: This study was aimed to investigate the association between amisulpride-induced hyperprolactinemia and the Taq1A polymorphism in the D2 dopamine receptor gene (DRD2) in schizophrenic patients. METHODS: The plasma concentrations of...
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Escitalopram-Induced Amenorrhea and False Positive Urine Pregnancy Test

Selvaraj V, Hour S, Gunasekar , Gray C, Smith JF

Escitalopram is a selective serotonin reuptake inhibitor antidepressant approved by the Food and Drug Administration for the treatment of major depressive disorder and generalized anxiety disorder. A 34-year-old female patient...
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Effects of Antipsychotics on Bone Mineral Density in Patients with Schizophrenia: Gender Differences

Chen CY, Lane HY, Lin CH

Low bone mineral density (BMD) and osteoporosis are common in patients with schizophrenia and detrimental to illness prognosis and life quality. Although the pathogenesis is not fully clear, series of...
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Different Responses of Aripiprazole Combination Treatment in Antipsychotics-Induced Hyperprolactinemia: 2 Cases

Cho JW, Oh SM, Kim CE

Hyperprolactinemia is a well-known neuroendocrine side effect to antipsychotic agent. Combined treatment of aripiprazole is recognized as an effective solution against hyperprolactinemia caused by antipsychotic agent. We report 2 progressive...
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Emerging Hyperprolactinemic Galactorrhea in Obsessive Compulsive Disorder with a Stable Dose of Fluoxetine

Chatterjee SS, Mitra S, Mallik N

While fluoxetine (FXT) is a frequently prescribed selective serotonin reuptake inhibitor (SSRI), with few major side-effects; altered serotonergic transmissions in hypothalamic pathways might lead to a distressing, and often embarrassing,...
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One-Year Follow-Up of Serum Prolactin Level in Schizophrenia Patients Treated with Blonanserin: A Case Series

Takahashi , Suzuki M, Uchiyama M

In our previous study, a prolactin elevation was more frequently in risperidone than in blonanserin; however, it was more often in blonanserin than in olanzapine. Therefore, while a rate of...
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The Short-Term Effects of Risperidone-Induced Hyperprolactinemia on Lipid Metabolism in Drug-Naive Children and Adolescents

Park EJ, Park YM

OBJECTIVE: The present cross-sectional study was designed to assess the risk of elevated prolactin levels and other hormonal or metabolic changes in children and adolescents taking risperidone. METHODS: Twenty-five children and...
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Early Prediction of Long-Term Response to Cabergoline in Patients with Macroprolactinomas

Lee Y, Ku CR, Kim EH, Hong JW, Lee EJ, Kim SH

BACKGROUND: Cabergoline is typically effective for treating prolactinomas; however, some patients display cabergoline resistance, and the early characteristics of these patients remain unclear. We analyzed early indicators predicting long-term response...
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Korean Medication Algorithm for Bipolar Disorder 2014: Safety and Tolerability

Sohn I, Kim MD, Lee JG, Yoon BH, Jeong JH, Shim SH, Woo YS, Seo JS, Shin YC, Min KJ, Bahk WM, Jon DI

OBJECTIVE: The complexity of the treatment for bipolar disorder is often caused by the presence of side effects of various psychiatric medications. In particular, weight gain and metabolic syndrome are...
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Granulomatous Mastitis during Chronic Antidepressant Therapy: Is It Possible a Conservative Therapeutic Approach?

Bellavia M, Damiano G, Palumbo VD, Spinelli G, Tomasello , Marrazzo A, Ficarella , Bruno A, Sammartano A, Fiorentini T, Scio A, Maione C, Lo Monte A

Granulomatous mastitis is a rare benign inflammatory disease of the breast with multiple etiologies such as tuberculosis, sarcoidosis, foreign body reaction, and mycotic and parasitic infections. In contrast, idiopathic granulomatous...
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Diagnosis and Treatment of Hyperprolactinemia

Kim M

  • KMID: 2329561
  • J Reprod Endocrinol.
  • 2012 Oct;4(2):83-90.
Hyperprolactinemia is a common cause of reproductive problems encountered clinical practice. It is more frequent in women, but also seen in men and even in adolescence and childhood. A variety...
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Comparison of Efficacy and Side Effects between Aripiprazole and Haloperidol in the Treatment of Delirium

Lee SH, Park SJ

  • KMID: 2334132
  • J Korean Geriatr Psychiatry.
  • 2011 Jun;15(1):31-37.
OBJECTIVES: To compare the efficacy and the safety of aripiprazole and haloperidol in the treatment of patients with delirium. METHODS: 26 patients with delirium were randomized to receive either aripiprazole or...
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Amisulpride-Induced Hyperprolactinemia:Preliminary Study

Lee JW, Park YM, Lee SH, Kang SG, Lee BH, Park E

  • KMID: 1445936
  • Korean J Psychosom Med.
  • 2011 Jun;19(1):41-47.
OBJECTIVE: Hyperprolactinemia is common side effect associated with antipsychotics use. Nevertheless, hyperprolactinemia is relatively neglected by clinician. Especially, there is no study related to amisulpride-induced hyperprolactinemia in korea. This study...
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Hyperprolactinemia-Associated Breast Uptake of Radioiodine Following 131I Postablation Scan in Differentiated Thyroid Cancer

Ahn JH, Kim SY, Kim YJ, Lee SY, Lee JH, Kang SH, Hong HC, Yang SJ, Yoo HJ, Seo JA, Kim SG, Kim NH, Choi KM, Baik SH, Choi DS, Choi HY

Scanning with whole-body 131I scintigraphy after surgery has been a valuable diagnostic modality in the surveillance of patients with differentiated thyroid cancer. Radioiodine uptake is rarely observed in non-lactating breast...
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A Case of Paroxetine-Related Hyperprolactinemia

Baek DU, Cho MA, Jae YM

  • KMID: 2287387
  • Korean J Psychopharmacol.
  • 2010 Apr;21(2):99-103.
Although selective serotonin reuptake inhibitors (SSRIs) have been widely used in both psychiatry and other medicine, few cases have been reported SSRI-related hyperprolactinemia and/or galactorrhea. We experienced one case which...
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