Ann Clin Microbiol.  2018 Sep;21(3):64-67. 10.5145/ACM.2018.21.3.64.

Nocardia abscessus Cutaneous Abscess: A Case Report and Review of the Literature

Affiliations
  • 1Department of Laboratory Medicine, Chungbuk National University Hospital, Cheongju, Korea.
  • 2Department of Laboratory Medicine, Chungbuk National University College of Medicine, Cheongju, Korea. ksshin@chungbuk.ac.kr
  • 3Department of Microbiology, Chungbuk National University College of Medicine, Cheongju, Korea.

Abstract

We describe a cutaneous abscess caused by Nocardia abscessus in a previously healthy woman. A 74-year-old woman presented with recurrent bullae on her left forearm that developed 1 week prior and was initially suspected to be a cutaneous infection with Mycobacteria or Tinea corporis. Histopathologically, the skin lesion formed an abscess. A smear revealed a few branched Gram-positive filamentous microorganisms that formed a creamy white colony on a blood agar plate after incubation for 3 days. The colony tested negative on acid-fast bacilli (AFB) staining, but was positive on modified AFB staining. The isolate was confirmed to be N. abscessus by 16S rRNA sequencing analysis. The isolate was susceptible to trimethoprim-sulfamethoxazole, amikacin, cefotaxime and erythromycin but resistant to penicillin. The patient was treated with clarithromycin but subsequently lost to follow-up. To the best of our knowledge, this is the first report of a human cutaneous infection with N. abscessus in Korea.

Keyword

Cutaneous abscess; Nocardia abscessus; 16S rRNA sequence

MeSH Terms

Abscess*
Agar
Aged
Amikacin
Cefotaxime
Clarithromycin
Erythromycin
Female
Forearm
Humans
Korea
Lost to Follow-Up
Nocardia*
Penicillins
Skin
Tinea
Trimethoprim, Sulfamethoxazole Drug Combination
Agar
Amikacin
Cefotaxime
Clarithromycin
Erythromycin
Penicillins
Trimethoprim, Sulfamethoxazole Drug Combination
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