J Dent Anesth Pain Med.  2018 Aug;18(4):261-265. 10.17245/jdapm.2018.18.4.261.

Use of sugammadex in Rett syndrome: A case report

• Kupeli I
• Tepe E
• Kuyrukluyıldız U

• KMID: 2419068
• DOI: http://doi.org/10.17245/jdapm.2018.18.4.261

Abstract

Rett syndrome (RS) is a neurodevelopmental disorder characterized by loss of cognitive, motor, and social skills, epilepsy, autistic behavior, abnormal airway patterns, gastroesophageal reflux, nutritional problems, and severe scoliosis. Although girls with RS show normal or near-normal growth until 6-8 months, they lose their skills after that. The anesthetic management of these patients requires care because of all these clinical features. Especially in the postoperative period, prolonged apnea is common and extubation is delayed. In this case report, the effect of using sugammadex was presented in a 16-year-old girl with RS. The patient's all bimaxillary teeth and 4 wisdom teeth were extracted under general anesthesia in one session with minimal surgical trauma and moderate bleeding. Sugammadex can be a rapid and reliable agent for the reversal of the neuromuscular block in neurodegenerative patients.

Keyword

General Anesthesia; Rett Syndrome; Sugammadex

MeSH Terms

Adolescent
Anesthesia, General
Apnea
Epilepsy
Female
Gastroesophageal Reflux
Hemorrhage
Humans
Molar, Third
Neurodevelopmental Disorders
Neuromuscular Blockade
Postoperative Period
Rett Syndrome*
Scoliosis
Social Skills
Tooth

Figure

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  Fig. 1 The patient's hands and legs

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  Fig. 2 Electrocardiograph

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