- Effect of patient decision aids on choice between sugammadex and neostigmine in surgeries under general anesthesia: a multicenter randomized controlled trial
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Wang LK, Lin YT, Chen JT, Lan W, Hung KC, Chen JY, Liu KJ, Yen YC, Chou YY, Cherng YG, Tam KW
- KMID: 2544547
- Korean J Anesthesiol.
- 2023 Aug;76(4):280-289.
- doi: 10.4097/kja.22624
Background: Shared decision making using patient decision aids (PtDAs) was established over a decade ago, but few studies have evaluated its efficacy in Asian countries. We therefore evaluated the application... -
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- What we need to know and do on sugammadex usage in pregnant and lactating women and those on hormonal contraceptives
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Do W, Cho AR
- KMID: 2543652
- Anesth Pain Med.
- 2023 Apr;18(2):114-122.
- doi: 10.17085/apm.23041
Sugammadex is a chemically modified γ-cyclodextrin that is used as a selective reversal agent for steroidal neuromuscular blockade. The use of sugammadex has greatly increased globally; however, little is known... -
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- Evaluation of the effects of bupivacaine combined with sugammadex on the duration of the nociceptive blockade in sciatic nerve blocks: a controlled, double-blind animal study
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Tasargol O, Darbaz I, Ergene O, Zabitler F, Deniz A, Kose SG, Kose HC, Tulgar S
- KMID: 2541005
- Korean J Anesthesiol.
- 2023 Apr;76(2):152-159.
- doi: 10.4097/kja.22486
Background: Animal and other experimental studies have demonstrated increased block time and quality when α- and β-cyclodextrin drugs are combined with local anesthetics. However, to our knowledge, no study has... -
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- Cardiac arrest due to coronary vasospasm after sugammadex administration -a case report-
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Boo KY, Park SH, Park SK, Na C, Kim HJ
- KMID: 2538892
- Korean J Anesthesiol.
- 2023 Feb;76(1):72-76.
- doi: 10.4097/kja.22335
Backgroud: Sugammadex is a widely used medication for the reversal of aminosteroid neuromuscular blockades. Although sugammadex is generally regarded to be safe, concerns about the risk of serious complications have... -
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- Sugammadex administration in patients with end-stage renal disease: a narrative review with recommendations
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Oh SK, Lim BG
- KMID: 2540329
- Anesth Pain Med.
- 2023 Jan;18(1):11-20.
- doi: 10.17085/apm.22259
Due to unknown safety concerns, sugammadex should not be administered to patients withend-stage renal disease (ESRD). However, because the supply of benzylisoquinolinium-typeneuromuscular blocking agents (NMBAs) has been discontinued, rocuronium is... -
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- Does the Use of Rocuronium-Sugammadex Instead of Succinylcholine in Electroconvulsive Therapy Affect Seizure Duration?
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Oflezer C, Atay Ö, Kaşdoğan ZE, Özakay G, İpekçioğlu D, Bahadır H
- KMID: 2535969
- Psychiatry Investig.
- 2022 Oct;19(10):824-831.
- doi: 10.30773/pi.2022.0123
Objective We compared retrospectively the seizure variables of electroconvulsive therapy (ECT) patients after administration of rocuronium-sugammadex or succinylcholine as a muscle relaxant with propofol anesthesia. Methods The sample comprised 134 ECT... -
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- Postoperative mortality in patients with end-stage renal disease according to the use of sugammadex: a single-center retrospective propensity score matched study
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Song S, Cho HB, Park SY, Koo WM, Choi SJ, Yoon S, Park S, Yoo JH, Kim MG, Chung JW, Kim SH
- KMID: 2535335
- Anesth Pain Med.
- 2022 Oct;17(4):371-380.
- doi: 10.17085/apm.22189
excretion. There are restrictions on the use of sugammadex in patients with severe renal impairment. A paucity of data supports the clinical safety of sugammadex in patients with renal impairment.... -
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- Choice of neuromuscular block reversal agent to reduce postoperative pulmonary complications
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Cho SA, Sung TY
- KMID: 2531688
- Anesth Pain Med.
- 2022 Apr;17(2):121-131.
- doi: 10.17085/apm.22146
The definition of postoperative pulmonary complications (PPCs) is inconsistent in literature; however, PPCs include pulmonary abnormalities that adversely affect patient outcomes, such as respiratory failure, atelectasis, pneumonia, pleural effusion, and... -
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- Adverse events of sugammadex that occurred in a Korean population
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Han W, Lee JM, Park DH, Lee CA, Jeong CY, Yang HS
- KMID: 2531695
- Anesth Pain Med.
- 2022 Apr;17(2):191-198.
- doi: 10.17085/apm.21096
Background: With increasing use, the incidence of adverse events associated with sugammadex, a neuromuscular blockade reverser, is increasing. This study aimed to identify and analyze cases of adverse events caused... -
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- Effects of hydrocortisone-presensitized sugammadex on recovery from neuromuscular blockade induced by rocuronium: a rodent in vivo study
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Choi HR, Yang HS, Choi JM, Park C, In J, Kim YB
- KMID: 2531694
- Anesth Pain Med.
- 2022 Apr;17(2):182-190.
- doi: 10.17085/apm.21076
Background: Sugammadex is a specific antagonist of aminosteroidal neuromuscular blocking agents with 1:1 binding to guest molecules. Sugammadex can also bind to other drugs having a steroid component in its... -
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- The use of sugammadex in an infant with prolonged neuromuscular blockade - A case report -
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Kim H, Cho J, Lee S, Lim Y, Yoo B
- KMID: 2526527
- Anesth Pain Med.
- 2022 Jan;17(1):52-56.
- doi: 10.17085/apm.21071
Background: Residual neuromuscular blockade (RNMB) is a frequent event after general anesthesia, which can lead to serious complications, such as upper airway obstruction. Sugammadex is useful in reversing RNMB. However,... -
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- Successful Anesthetic Management of Myotonic Dystrophy Type I Using Sugammadex: A Case Report
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Kim S, Chun HR, Chung J
- KMID: 2524027
- Soonchunhyang Med Sci.
- 2021 Dec;27(2):125-128.
- doi: 10.15746/sms.21.031
Myotonic dystrophy (DM) is an uncommon inherited disease. Anesthesia for DM patients is tough due to its potency of cardiogenic and pulmonary problems, but a series of studies have shown... -
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- Comparison of postoperative pulmonary complications between sugammadex and neostigmine in lung cancer patients undergoing video-assisted thoracoscopic lobectomy: a prospective double-blinded randomized trial
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Lee TY, Jeong SY, Jeong JH, Kim JH, Choi SR
- KMID: 2512283
- Anesth Pain Med.
- 2021 Jan;16(1):60-67.
- doi: 10.17085/apm.20056
Background: Reversal of neuromuscular blockade (NMB) at the end of surgery is important for reducing postoperative residual NMB; this is associated with an increased risk of postoperative pulmonary complications (PPCs).... -
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- Treatment of rocuronium-induced anaphylaxis using sugammadex - A case report -
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Kim SM, Oh Sh, Ryu SA
- KMID: 2512282
- Anesth Pain Med.
- 2021 Jan;16(1):56-59.
- doi: 10.17085/apm.20074
Background: Perioperative anaphylaxis is a life-threatening clinical condition characterized by severe respiratory and cardiovascular manifestations. Neuromuscular blocking agents are the most common cause of anaphylaxis during anesthesia. Case: We report... -
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- Anaphylaxis induced by sugammadex and sugammadex-rocuronium complex -a case report-
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Choi SC, Han S, Kwak J, Lee JY
- KMID: 2505113
- Korean J Anesthesiol.
- 2020 Aug;73(4):342-346.
- doi: 10.4097/kja.19344
Background: In sugammadex-induced anaphylaxis, sugammadex and/or sugammadex-rocuronium complex have possible allergenic epitope. Case: We report a case of sugammadex-induced anaphylaxis during general anesthesia in a 60-year-old male undergoing... -
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- Advantages and pitfalls of clinical application of sugammadex
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Lee HY, Jung KT
- KMID: 2504886
- Anesth Pain Med.
- 2020 Jul;15(3):259-268.
- doi: 10.17085/apm.19099
Sugammadex, a modified γ-cyclodextrin, is one of the drugs focused on in the anesthetic field because it provides rapid and complete reversal from neuromuscular blockade (NMB) by encapsulating rocuronium. Its... -
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- Effects of different sugammadex doses on the train of four ratio recovery progression during rocuronium induced neuromuscular blockade in the rat phrenic nerve hemidiaphragm
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Kim YB, Choi JM, Chang YJ, Choi HR, In J, Yang HS
- KMID: 2503128
- Korean J Anesthesiol.
- 2020 Jun;73(3):239-246.
- doi: 10.4097/kja.19278
Background: In this study, we used an ex-vivo model to investigate the recovery pattern of both the train-of-four (TOF) ratio and first twitch tension of TOF (T1), and determined their... -
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- The effect of atropine in preventing catheter-related pain and discomfort in patients undergoing transurethral resection due to bladder tumor; prospective randomized, controlled study
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Şahiner Y, Yağan , Ekici AA, Ekici M, Demir E
- KMID: 2502641
- Korean J Pain.
- 2020 Apr;33(2):176-182.
- doi: 10.3344/kjp.2020.33.2.176
Background: Catheter-related bladder discomfort (CRBD) has been observed in many patients undergoing a urethral catheterization. CRBD may be so severe that the patients require additional analgesics. Muscarinic receptors are involved... -
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- Neuromuscular blockade reversal with sugammadex versus pyridostigmine/ glycopyrrolate in laparoscopic cholecystectomy: a randomized trial of effects on postoperative gastrointestinal motility
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An J, Noh H, Kim E, Lee J, Woo K, Kim H
- KMID: 2501819
- Korean J Anesthesiol.
- 2020 Apr;73(2):137-144.
- doi: 10.4097/kja.19360
Background: Acetylcholinesterase inhibitors (e.g., pyridostigmine bromide) are used for neuromuscular blockade (NMB) reversal in patients undergoing surgery under general anesthesia (GA). Concurrent use of anticholinergic agents (e.g., glycopyrrolate) decreases cholinergic... -
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- Evaluation of the Toxicity of Sugammadex in Zebrafish Larvae
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Kim WY, Kim YH, Lee JY, Kim JH, Min TJ
- KMID: 2471204
- J Korean Med Sci.
- 2020 Mar;35(9):e51.
- doi: 10.3346/jkms.2020.35.e51
BACKGROUND: Sugammadex is a new neuromuscular blockade reversal agent. Recently, it has been used in patients under general anesthesia. However, sugammadex could be toxic to fetuses and pediatric patients under... -
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