J Korean Soc Radiol.  2018 Jun;78(6):408-411. 10.3348/jksr.2018.78.6.408.

Early Evaluation of Inflammatory Focus and Treatment Response Using ¹⁸F-Sodium Fluoride Bone Positron Emission Tomography/Computed Tomography in Patients with Metallic Implants: A Case Report

Affiliations
  • 1Department of Radiology, Soonchunhyang University Cheonan Hospital, Cheonan, Korea.
  • 2Department of Nuclear Medicine, Soonchunhyang University Cheonan Hospital, Cheonan, Korea. gareen@naver.com
  • 3Department of Orthopedic Surgery, Soonchunhyang University Cheonan Hospital, Cheonan, Korea.
  • 4Department of Nuclear Medicine, Catholic Kwandong University College of Medicine, International St. Mary's Hospital, Incheon, Korea.

Abstract

We report a case of a 76-year-old woman with elevated serum C-reactive protein levels for two weeks after spinal surgery. ⁹⁹mTc-labeled white blood cell scan and dual ¹â¸F-sodium-fluoride (¹â¸F-NaF) bone positron emission tomography/computed tomography (PET/CT) were used to detect the site of inflammation. Using non-attenuation corrected images, soft tissue inflammation was detected without metal artifact. Antibiotic treatment attenuated inflammation as seen in an early-phase scan using follow-up ¹â¸F-NaF bone PET/CT. This case demonstrates the role of ¹â¸F-NaF bone PET/CT in the detection of inflammation sites, and can be used to evaluate treatment response in patients with metallic implants.


MeSH Terms

Aged
Artifacts
C-Reactive Protein
Electrons*
Female
Fluorides*
Follow-Up Studies
Humans
Inflammation
Leukocytes
Positron-Emission Tomography and Computed Tomography
Sodium Fluoride
Treatment Outcome
C-Reactive Protein
Fluorides
Sodium Fluoride
Full Text Links
  • JKSR
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
    DB Error: unknown error