Nucl Med Mol Imaging.  2017 Sep;51(3):271-273. 10.1007/s13139-016-0400-6.

⁶⁸Gallium-Arginine-Glycine-Aspartic Acid and ¹⁸F-Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography in Chondroblastic Osteosarcoma of the Skull

• Orunmuyi A
• Modiselle
• Lengana T
• Ebenhan T
• Vorster M
• Sathekge M

• KMID: 2396588
• DOI: http://doi.org/10.1007/s13139-016-0400-6

Abstract

We report the case of a 32 year-old male with Chondroblastic Osteosarcoma of the skull, which was imaged with both ¹â¸[F]fluorodeoxyglucose (¹â¸F-FDG) positron emission tomography/computed tomography (PET/CT) and ⁶⁸Gallium-arginine-glycine-aspartic acid (⁶⁸Ga-RGD) PET/CT. The ¹â¸F-FDG PET/CT did not demonstrate the tumour,whereas the ⁶⁸Ga-RGD PET/CT clearly depicted a left-sided frontal tumour. ⁶⁸Ga-RGD PET/CT may be a clinically useful imaging modality for early detection of recurrent osteosarcoma, considering the limitations of ¹â¸F-FDG PET in a setting of low glycolytic activity.

Keyword

Chondroblastic Osteosarcoma; ¹⁸F-FDG; ⁶⁸Ga-RGD; PET/CT

MeSH Terms

Chondrocytes*
Electrons*
Humans
Male
Osteosarcoma*
Positron-Emission Tomography and Computed Tomography
Skull*