Asia Pac Allergy.  2016 Apr;6(2):129-132. 10.5415/apallergy.2016.6.2.129.

A case study of apple seed and grape allergy with sensitisation to nonspecific lipid transfer protein

• Murad A
• Katelaris
• Baumgart K

• KMID: 2396982
• DOI: http://doi.org/10.5415/apallergy.2016.6.2.129

Abstract

Lipid transfer proteins can be an important cause of allergy given their stability and high degree of protein sequence homology. We describe the case of a child who developed two separate episodes of anaphylaxis after consuming apple seed and grape, with evidence that nonspecific lipid transfer proteins may have been responsible for these reactions. Lipid transfer protein allergy should be considered when anaphylaxis is inconsistent, such as in patients who can tolerate fruit pulp but react to fresh whole fruit juices.

Keyword

Seeds; Allergy; Anaphylaxis; Lipid transfer protein

MeSH Terms

Anaphylaxis
Child
Fruit
Fruit and Vegetable Juices
Humans
Hypersensitivity*
Sequence Homology, Amino Acid
Vitis*

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