Korean J Dermatol.  2017 Aug;55(7):449-453.

Candida famata Infection Presenting as an Erosive Patch on the Sole of an Immunocompetent Patient

• Park BJ
• Choi HS
• Park HK
• Kim YG
• Kim JS
• Yu HJ

Abstract

Candida famata previously called Torulopsis famata or Debaryomyces hansenii, is usually found in natural substrates. It was earlier considered nonpathogenic in humans; however, a number of clinical cases of human infection have been reported showing isolation of this yeast. Dermatologic literature contains only a few reports regarding cutaneous infection caused by Candida famata. An 18-year old woman presented with a 4-month history of a 4.0×3.0 cm sized erythematous erosive patch on her left sole. A skin biopsy revealed numerous spores and hyphae in the epidermis. Histopathological specimens showed positive findings using the Periodic acid-Schiff and Gomori methenamine silver stains but negative findings using acid-fast bacilli stain. Cultures from skin scrapings yielded numerous colonies. Identification of the fungus was processed up to species level using VITEK 2 (bioMérieux, Inc. Hazelwood, MO, USA), and Candida famata was isolated. She was administered itraconazole at a dose of 200 mg once daily, and following 5 weeks of therapy, the erosive lesion was noted to have completely healed with postinflammatory hyperpigmentation.

Keyword

Candida famata; Cutaneous candidiasis

MeSH Terms

Biopsy
Candida*
Candidiasis, Cutaneous
Coloring Agents
Epidermis
Female
Fungi
Humans
Hyperpigmentation
Hyphae
Itraconazole
Methenamine
Skin
Spores
Yeasts
Coloring Agents
Itraconazole
Methenamine