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Posaconazole versus Itraconazole as Prophylactic Antifungal Agents during Induction Chemotherapy for Acute Myeloid Leukemia: A Real-World Single Center Comparison

Kim C, Yoon SY, Lee MY, Kim KH, Lee N, Won JH

OBJECTIVE: To prevent invasive fungal disease (IFD) in acute myeloid leukemia (AML) patients, the use of posaconazole as a prophylactic antifungal agent has become standard in patients undergoing induction chemotherapy....
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A Case of Subcutaneous and Intranasal Phaeohyphomycosis Caused by Microsphaeropsis arundinis in an Immunocompromised Patient Misdiagnosed with Mucormycosis

Choi H, Kim CJ, Kim MS, Shin BS, Na CH

Microsphaeropsis arundinis is a dematiaceous fungus capable of causing soft tissue infections known as phaeohyphomycosis, mostly in immunocompromised individuals. These infections arise from the traumatic inoculation of fungal materials into...
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Unusual Presentation of Subcutaneous Phaeohyphomycosis by Alternaria alternate

Lee JY, Hyun M, Kim HA, Ryu SY

The Alternaria species are dematiaceous fungi. Human infection due to dematiaceous fungi is uncommon. Most reported cases of alternariosis have occurred in patients with immunodeficiency. The majority of cases were...
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Fungal Melanonychia Caused by Cladosporium Species: A Case Report

Yoon JH, An MK, Park EJ, Kim KH, Kim KJ

Fungal melanonychia is typically associated with onychomycosis and is known to be a relatively uncommon nail disorder. The known pathogens causing fungal melanonychia include both dematiaceous and non-dematiaceous fungi. Here...
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A Case of Deep Cutaneous Purpureocillium lilacinum Fungal Infection in an Immunocompetent Patient

Kim H, Cho GJ, Kim JU, Jin WJ, Park SH, Moon SH, Seol JE, Shin JH

Purpureocillium is a genus of saprophytic fungi that is commonly found in soil or rotting material. Although rarely a pathogen in humans, it can cause serious infections in immunocompromized patients....
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A Descriptive Review of Kerion and Non-inflammatory Tinea Capitis

Kim SM, Kim YA, Cho NJ

  • KMID: 2449199
  • Korean J Dermatol.
  • 2019 May;57(4):182-190.
BACKGROUND: Tinea capitis manifests either as a non-inflammatory or inflammatory type including kerion, which may cause permanent alopecia. In addition to antifungals, systemic corticosteroids (prednisolone at 1~2 mg/kg/day) have been...
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Current state and outlook for drug repositioning anticipated in the field of ovarian cancer

Kobayashi , Banno K, Kunitomi H, Tominaga E, Aoki D

Ovarian cancer is the seventh most common cancer and the eighth most common cause of cancer mortality in women. Although standard chemotherapy is the established treatment for ovarian cancer, the...
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Evaluation of the Interventional Approaches in the Management of Cutaneous Leishmaniasis in Jazan: An Observational Study

Makeen HA, Buraik MA, Menachery , Alattas KM, Meraya AM

BACKGROUND: Cutaneous leishmaniasis is a tropical infection of public health importance. Numerous treatment approaches are in practice with variable degree of success however its management has no universal consensus or...
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Imidazole Antifungal Drugs Inhibit the Cell Proliferation and Invasion of Human Breast Cancer Cells

Bae SH, Park JH, Choi HG, Kim H, Kim SH

Breast cancer is currently the most prevalent cancer in women, and its incidence increases every year. Azole antifungal drugs were recently found to have antitumor efficacy in several cancer types....
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Familial Sporotrichosis Due to Human-to-human Infection of Sporothrix globosa: A Case Report

Kim JG, Kim HR, You MH, Shin DH, Choi JS

Typically, sporotrichosis follows an environmental transmission route via traumatic inoculation of contaminated plant or soil matter. Although familial occurrences of sporotrichosis are rare, human-to-human transmission is even rarer. Herein, we...
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Catheter-Related Trichosporon asahii Bloodstream Infection in a Neutropenic Patient with Myelodysplastic Syndrome

Go SE, Lee KJ, Kim Y, Choi JK, Kim YJ, Lee DG

Because primary antifungal prophylaxis is widely used for immunocompromised hosts, the incidences of unusual fungal infections have increased. Trichosporon asahii has emerged as an important life-threatening opportunistic systemic pathogen because...
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A Diabetic Elderly Man with Finger Ulcer

Mohamad N, Badrin S, Wan Abdullah WNH

Fixed cutaneous sporotrichosis is a differential diagnosis that can be considered in diabetic patients who present with a poorly healing ulcer. Although its prevalence is low, it can occur in...
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Pulmonary Histoplasmosis Identified by Video-Assisted Thoracic Surgery (VATS) Biopsy: a Case Report

Lee YJ, Kang HR, Song JH, Sin S, Lee SM

Histoplasmosis is a common endemic mycosis in North, Central, and South America, but Korea is not known as an endemic area. We treated an immunocompetent Korean patient who had histoplasmosis....
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Antiviral Activity of Itraconazole against Echovirus 30 Infection In Vitro

Lee JS, Choi HJ, Song JH, Ko HJ, Yoon K, Seong JM

OBJECTIVES: Echovirus 30 is a major cause of meningitis in children and adults. The aim of this study was to investigate whether the antifungal drug itraconazole could exhibit antiviral activity...
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Candida famata Infection Presenting as an Erosive Patch on the Sole of an Immunocompetent Patient

Park BJ, Choi HS, Park HK, Kim YG, Kim JS, Yu HJ

  • KMID: 2391168
  • Korean J Dermatol.
  • 2017 Aug;55(7):449-453.
Candida famata previously called Torulopsis famata or Debaryomyces hansenii, is usually found in natural substrates. It was earlier considered nonpathogenic in humans; however, a number of clinical cases of human...
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A Case of Multiple Fungal Abscesses on Inguinal Area Caused by Itraconazole-resistant Trichophyton rubrum

Kang HJ, Won CH, Chang SE, Lee MW, Choi JH, Lee WJ

  • KMID: 2388336
  • Korean J Dermatol.
  • 2017 Jul;55(6):360-363.
Dermatophytes usually infect keratinized epithelial structures such as hair and nails. However, they can also cause deep and extensive fungal infections, especially in immunocompromised patients. We report a case with...
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A Case of Tinea Incognito Mimicking Folliculitis in Atopic Dermatitis Patient

Shin YS, Park BW, Cho EB, Park EJ, Kim KH, Kim KJ

A 27-year-old male with underlying history of atopic dermatitis presented with skin lesion on the trunk and upper extremity, occurring a month ago. Scattered erythematous multiple tiny maculopapules and patches...
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A Case of Subcutaneous Phaeohyphomycosis Caused by Exophiala oligosperma Showing Multiple Cysts

Ryu TH, Kwon IH, Choi JE, Ahn HH, Kye YC, Seo SH

  • KMID: 2379903
  • Korean J Dermatol.
  • 2017 May;55(4):259-263.
Exophiala species are dark pigmented fungi associated with phaeohyphomycosis that exhibit yeast-like or hyphal forms of the fungus in superficial subcutaneous locations or systemic disease. The incidence of subcutaneous tissue...
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Tinea Versicolor Mimicking Pityriasis Rubra Pilaris caused by Malassezia globosa

Bae SH, Lee MY, Lee JB

Tinea versicolor (TV) is a common fungal skin disease caused by the Malassezia species. This disease usually presents as hypopigmented- or hyperpigmented coalescing scaly macules, papules, patches or plaques on...
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In vitro Susceptibility of the Six Malassezia Species to Itraconazole, Fluconazole and Terbinafine

Lee Y

BACKGROUND: Malasseiza species are dimorphic and lipophilic fungi which are part of normal mycota of the human skin, and also associated with some skin diseases. In many skin diseases such...
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