Korean J Intern Med.
2015 Sep;30(5):665-674. 10.3904/kjim.2015.30.5.665.
Time points for obtaining representative values of 24-hour blood pressure in chronic kidney disease
- Affiliations
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- 1Department of Internal Medicine, Hallym University College of Medicine, Chuncheon, Korea.
- 2Department of Internal Medicine, National Medical Center, Seoul, Korea.
- 3Department of Internal Medicine, Soonchunhyang University College of Medicine, Cheonan, Korea.
- 4Medical Research Collaborating Center, Seoul National University Bundang Hospital, Seongnam, Korea. sejoong2@snu.ac.kr
- 5Department of Internal Medicine, College of Medicine, Uijeongbu St. Mary's Hospital, The Catholic University of Korea, Uijeongbu, Korea.
- 6Department of Internal Medicine, Ewha Womans University School of Medicine, Seoul, Korea.
- 7Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI, USA.
- 8Department of Internal Medicine, Inje University College of Medicine, Goyang, Korea.
- 9Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.
- KMID: 2381565
- DOI: http://doi.org/10.3904/kjim.2015.30.5.665
Abstract
- BACKGROUND/AIMS
Ambulatory blood pressure (BP) monitoring has been widely recommended for evaluating the status of BP, but is lacking in practicality. Determination of the specific time points for BP measurement that are representative of 24-hour mean BP could be useful and convenient in hypertensive patients with chronic kidney disease (CKD).
METHODS
A total of 1,317 patients for whom 24-hour ambulatory BP monitoring was performed were enrolled in a multicenter study on hypertensive CKD. We analyzed the time points at which systolic blood pressure (SBP) values exhibited the smallest differences from 24-hour mean SBP (mSBP). We included office mSBP and analyzed the relationships between SBPs at the office and the time points with the smallest differences from 24-hour mSBP using several methods.
RESULTS
The time points with the smallest differences from 24-hour mSBP were 7:00 AM, 2:00 PM, and 9:30 PM. In regression analysis, SBPs at 7:00 AM and 9:30 PM were better correlated with 24-hour mSBP than SBPs at 2:00 PM and the office. The proportions of patients with SBPs within 30% of 24-hour mSBP were higher at 7:00 AM and 9:30 PM. The best consistency between the uncontrolled hypertensive groups, defined as > or = 135 mmHg of 24-hour mSBP and higher values of SBPs corresponding to 135 mmHg of 24-hour mSBP, were observed at the 7:00 AM and 9:30 PM time points.
CONCLUSIONS
The specific time points for SBPs that correlated well with 24-hour mSBP in hypertensive CKD patients were 7:00 AM and 9:30 PM.
Keyword
MeSH Terms
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Adult
Aged
*Blood Pressure
Blood Pressure Monitoring, Ambulatory/*methods
Circadian Rhythm
Cross-Sectional Studies
Female
Humans
Hypertension/*diagnosis/physiopathology
Male
Middle Aged
Office Visits
Predictive Value of Tests
Prospective Studies
Renal Insufficiency, Chronic/*diagnosis/physiopathology
Republic of Korea
Time Factors
Young Adult
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