Yeungnam Univ J Med.  1989 Dec;6(2):247-255. 10.12701/yujm.1989.6.2.247.

Polycythemia vera combined with coagulation disorder: A case report

Abstract

We report a case of polycythemia vera combined with coagulation disorder. The patient was 54 years old man who complained of continuous bleeding after incision of skin abscess 20days ago. Laboratory tests were revealed prolonged aPTT and slightly prolonged PT. Coagulation factor, I, VIII, IX, XI and fibrinogen decreased, however FDP did not increased. It appears that patient with polycythemia vera have chronic activation of coagulation system, probably initiated by activation of factor XII. Platelet aggregation test to ADP, collagen, epinephrine was also revealed poor response.


MeSH Terms

Abscess
Adenosine Diphosphate
Blood Coagulation Factors
Collagen
Epinephrine
Factor XII
Fibrinogen
Hemorrhage
Humans
Platelet Aggregation
Polycythemia Vera*
Polycythemia*
Skin
Adenosine Diphosphate
Blood Coagulation Factors
Collagen
Epinephrine
Factor XII
Fibrinogen
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