Korean J Dermatol.  2002 Jul;40(7):807-810.

A Case of Secondary Erythromelalgia Associated with Polycythemia Vera

• Jang SJ
• Park HS
• Lee YS
• Chun DK

Abstract

Erythromelalgia(EM) is a rare clinical syndrome characterized by the triad of redness, increased temperature, and pain of the extremities. The patient was a 69-year-old woman presented erythematous tender patches on both palms and soles. Laboratory and clinical investigations revealed an underlying myeloproliferative disorder. Histologic examination of the erythema on her foot showed some vessels with thickened endothelial walls and partially obstructed lumens by organized thrombi. Hydroxyurea used for the treatment of polycythemia vera eliminated the skin lesions and symptoms of erythromelalgia. We report a case of secondary erythromelalgia associated with polycythemia vera.

Keyword

Erythromelalgia; Polycythemia vera

MeSH Terms

Aged
Erythema
Erythromelalgia*
Extremities
Female
Foot
Humans
Hydroxyurea
Myeloproliferative Disorders
Polycythemia Vera*
Polycythemia*
Skin
Hydroxyurea