Korean J Anesthesiol.  2001 Dec;41(6):792-795. 10.4097/kjae.2001.41.6.792.

Epidural Block of Bupivacaine and Mexiletine for Erythromelalgia

• Park SK
• Han KR
• Lee YS
• Hyun HS
• Kim C

• KMID: 2091650
• DOI: http://doi.org/10.4097/kjae.2001.41.6.792

Abstract

Erythromelalgia is a rare disease characterized by palmar and plantar erythema, burning pain and local increase in temperature. Secondary erythromelalgia most commonly appears secondary to myeloproliferative disorders, essential thrombocytosis and polycythemia vera. The pain associated with erythromelalgia is often severe and recalcitrant. So far no properly performed therapeutic trials have been published. We present a case of erythromelalgia of both hands and feet in a 52 year old man. A twice daily cervical and lumbar epidural block of mepivacaine 0.5% and mexiletine 100 mg given orally resuletd in complete resolution of the syndrome. After 3 months, the symptom recurred mildly.

Keyword

Anesthetic techniques: epidural; Disease: erythromelalgia; Anesthetics, local: mepivacaine; Pharmacology: mexiletine

MeSH Terms

Bupivacaine*
Burns
Erythema
Erythromelalgia*
Foot
Hand
Humans
Mepivacaine
Mexiletine*
Middle Aged
Myeloproliferative Disorders
Polycythemia Vera
Rare Diseases
Thrombocytosis
Bupivacaine
Mepivacaine
Mexiletine