Res Vestib Sci.  2017 Mar;16(1):17-22. 10.21790/rvs.2017.16.1.17.

Usefulness Assessment of Cochlear Hydrops Analysis Masking Procedure Test in Progress of Ménière's Disease

• Ko YJ
• Kim HJ
• Kim DY
• Kyung TS
• Kim KS

• KMID: 2371822
• DOI: http://doi.org/10.21790/rvs.2017.16.1.17

Abstract

OBJECTIVE
There were few recent study concern about usefulness of cochlear hydrops analysis masking procedure (CHAMP) in progression of Ménière's disease. The purpose of this study is to analyze changes in the CHAMP as advancement of Ménière's disease.
METHODS
We studied 19 cases of "˜ Definite' group of Ménière's disease. We assumed progression of Ménière's disease would be checked by pure tone threshold by four tone average (4PTA), low tone average (LPTA). We also compared electrocochleography (ECoG), dizziness handicap inventory (DHI), tinnitus handicap inventory (THI) as parameters for progression of Ménière's disease to CHAMP latency delay and amplitude ratio. Chi-square test was used as a statistical method.
RESULTS
In the group of patients had abnormal amplitude ratio, ECoG value were not improved, but there was not statistically significant (odds ratio [OR]=5.727, p>0.05). Better DHI and THI score were not necessarily construed as the improvement value in the CHAMP (p>0.05). In amplitude ratio abnormal group, 4PTA was aggravated, but not statistically significant (OR=1.5, p>0.05). In the group of patient had abnormality in both latency delay and amplitude ratio, LPTA was relatively aggravated (OR in latency delay: 2, OR in amplitude ratio: 10); however, reveals no statistically significance between them (p>0.05). Change of ECoG, hearing threshold including 4PTA and LPTA with progression of Ménière's disease were not correlated significantly with latency delay or amplitude ratio of CHAMP.
CONCLUSION
We conclude that CHAMP does not reflect clinical features with progression of Ménière's disease.

Keyword

Dizziness; Vertigo; Ménière's disease; Endolymphatic hydrops; Hearing loss

MeSH Terms

Audiometry, Evoked Response
Dizziness
Edema*
Endolymphatic Hydrops
Hearing
Hearing Loss
Humans
Masks*
Meniere Disease*
Methods
Tinnitus
Vertigo