J Rheum Dis.  2017 Feb;24(1):35-42. 10.4078/jrd.2017.24.1.35.

Nutrient Intake in Postmenopausal Rheumatoid Arthritis Women with Osteoporosis: Results from the Korean National Health and Nutrition Examination Survey

• Baik YS
• Park JW
• Kim J
• Kim WG
• Oh S
• Cho SI
• Song YW
• Shin K

• KMID: 2371676
• DOI: http://doi.org/10.4078/jrd.2017.24.1.35

Abstract

OBJECTIVE
Osteoporosis (OP) is one of the principal comorbidities in women with rheumatoid arthritis (RA). Proper nutrition for these patients is required not only to improve bone health but to better manage their chronic illness. Thus, our aim was to assess the status of key nutrient intake in postmenopausal RA women with OP.
METHODS
Using cross-sectional data of 4,933 postmenopausal women in the Korean National Health and Nutrition Examination Survey (K-NHANES IV, V) conducted between 2008 and 2011, we investigated the daily nutrient intake in RA subjects and their bone mineral density (BMD). We examined the association of nutrient intake and BMD after adjusting age, level of education, body mass index, family history, alcohol use, and total calorie intake in the osteoporosis, osteopenia, and normal BMD group using multivariable linear regression.
RESULTS
We included 222 RA women and 320 controls whose BMD and T-score data were available. Low calcium and phosphorous intake were associated with reduced BMD T-scores in postmenopausal RA women. Additionally, β-carotene, potassium, riboflavin, and vitamin C intake were significantly lower in RA women with OP. Multivariable linear regression analysis showed a strong positive association of intake of β-carotene, potassium, riboflavin, and calcium with higher T-scores at the lumbar spine, femur neck, and total hip (all p<0.0001, respectively).
CONCLUSION
We found insufficient intake of nutrients such as β-carotene, potassium, riboflavin, and vitamin C in Korean postmenopausal RA women with low BMD. Dietary counseling and recommendations are warranted for these subjects to attain better bone health.

Keyword

Bone density; Nutrition surveys; Osteoporosis; Rheumatoid arthritis

MeSH Terms

Arthritis, Rheumatoid*
Ascorbic Acid
Body Mass Index
Bone Density
Bone Diseases, Metabolic
Calcium
Chronic Disease
Comorbidity
Counseling
Education
Female
Femur Neck
Hip
Humans
Linear Models
Nutrition Surveys*
Osteoporosis*
Potassium
Riboflavin
Spine
Ascorbic Acid
Calcium
Potassium
Riboflavin

Figure

• 

  Figure 1. Scheme of the study subject selection process. K-NHANES: Korean National Health and Nutrition Examination Survey, DXA: dual energy X-ray absorptiometry, RA: rheumatoid arthritis, OA: osteoarthritis, BMD: bone mineral density.

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