J Korean Med Sci.  2017 Mar;32(3):427-433. 10.3346/jkms.2017.32.3.427.

The Cut-off Values of Triglycerides and Glucose Index for Metabolic Syndrome in American and Korean Adolescents

• Moon S
• Park JS
• Ahn Y

• KMID: 2366638
• DOI: http://doi.org/10.3346/jkms.2017.32.3.427

Abstract

The aim of this study was to establish ethnic- and gender-specific cut-off values of triglycerides and glucose index (TyG index) for clinical usefulness in a representative sample of Mexican American, Non-Hispanic White, Non-Hispanic Black, and Korean adolescents. The data were collected from datasets of the National Health and Nutrition Examination Survey between 1999 and 2012, and the Korean National Health and Nutrition Examination Survey between 2005 and 2013. Receiver operating characteristic curve analysis was used to find valid cut-off values of the TyG index for metabolic syndrome. The total number of eligible participants was 3,164 in the US and 4,873 in Korea. The optimal cut-off value with the Cook et al. definition revealed 8.55 in Mexican American, 8.55 in Non-Hispanic White, 8.35 in Non-Hispanic Black, and 8.45 in Korean, respectively. The cut-off value with the de Ferranti et al. definition was 8.45, 8.45, 8.15, and 8.35, and the cut-off value with the International Diabetes Federation definition was 8.65, 8.65, 8.15, and 8.55, respectively. These findings may be clinically useful for evaluating insulin resistance for determining metabolic abnormalities in adolescents.

Keyword

Cardiovascular Disease; Insulin Resistance; Metabolic Syndrome; Nutrition Surveys; Triglycerides; Glucose; Insulin; Obesity; Adolescent; Child

MeSH Terms

Adolescent*
Cardiovascular Diseases
Child
Dataset
Glucose*
Humans
Insulin
Insulin Resistance
Korea
Mexican Americans
Nutrition Surveys
Obesity
ROC Curve
Triglycerides*
Glucose
Insulin
Triglycerides

Figure

• 

  Fig. 1 ROC curves for metabolic syndrome by ethnicity. (A) ROC curves for metabolic syndrome using the criteria of Cook et al. (21). (B) ROC curves for metabolic syndrome using the criteria of de Ferranti et al. (22). (C) ROC curves for metabolic syndrome using the criteria of IDF. ROC = receiver operating characteristic, IDF = International Diabetes Federation.

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