Korean J Anesthesiol.  1984 Jun;17(2):114-120.

Clinieal Effect of Thiopental-Thalamonal Induction During Intubation

• Chang TH
• Kim SH

Abstract

Induction of general anesthesia with tracheal intubation has several advantages but also causes some cardiovascular side effects. Several approaches have been tried to reduce these side effects. As an attempt to reduce elevated blood pressure and increased heart rate during tracheal intubation, we used thiopental 3 mg/kg with Thalamonal 0.05 mg/kg (experimental group II, 30 cases) as an induction of general anesthesia inatead of the conventional use of thiopental 6 mg/kg(control group I, 30 caaes). The results are as follows:1. Blood pressure and heart rate changes between the 2 gruops at postintubation 30 sec. were statistically significant; 194+/-24 torr, 111+/-15/min. in control gruop and 166+/-29 torr (p<0.01), 102+/-14/min. (p<0.05) in experimental group. 2. There were no significant changes in blood pressure and heart rate at pre-intubation and post-extubation period. 3. The incidence of tachycardia and arrhythmia were more frequent in the control group, while hypotension and severe respiratory depression in experimental group.

MeSH Terms

Anesthesia, General
Arrhythmias, Cardiac
Blood Pressure
Heart Rate
Hypotension
Incidence
Intubation*
Respiratory Insufficiency
Tachycardia
Thiopental
Thiopental