J Korean Neurol Assoc.
2003 Apr;21(2):199-203.
Primary Central Nervous System Lymphoma: A Notable Differential Diagnosis of Leukoencephalopathy
- Affiliations
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- 1Department of Neurology and Clinical Research Institute, Seoul National University Hospital, 28, Yongon-dong, Jongno-gu, Seoul, 100-744, Korea. kimmanho@snu.ac.kr
- 2Department of Neurology, lnje University Seoul Paik Hospital, Korea.
Abstract
- We report a 61-year-old man presented with hyperventilation in the absence of alteration of consciousness. Brain MRI showed diffuse T2-high signal intensities in the white matter of the bilateral hemispheres and brainstem with some focal enhancements without mass effect or edema. Methionine PET demonstrated hypermetabolism in the right thalamus and cerebellum. Primary central nervous system lymphoma (PCNSL) was confirmed pathologically by stereotaxic biopsy. PCNSL can take the form of leukoencephalopathy in MRI, and methionine PET would be helpful for the differentiation of PCNSL from non-tumorous conditions.
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