J Korean Neurol Assoc.  2009 Aug;27(3):286-290.

Primary Central Nervous System Lymphoma Diagnosed by Biopsy of Skin and Sural Nerve

Affiliations
  • 1Department of Neurology, Dongguk University International Hospital, Goyang, Korea. neukim@duih.org
  • 2Department of Pathology, Dongguk University International Hospital, Goyang, Korea.

Abstract

Primary central nervous system lymphoma (PCNSL) is a rare tumor that accounts for less than 2% of all cerebral neoplasms. A 72-year-old man had been suffering from recurrent cranial nerve palsies for several years. His condition improved with steroid treatment, but then eventually worsened; he developed encephalopathic symptoms, quadriparesis, axonal neuropathy, and skin lesions. He was eventually diagnosed with PCNSL following an examination of skin and sural nerve biopsy samples. Biopsy of skin lesions or nerves should be considered for the accurate and early diagnosis of PCNSL.

Keyword

Lymphoma; Peripheral nervous system; Skin

MeSH Terms

Aged
Axons
Biopsy
Central Nervous System
Cranial Nerve Diseases
Early Diagnosis
Humans
Lymphoma
Organic Chemicals
Peripheral Nervous System
Quadriplegia
Skin
Stress, Psychological
Sural Nerve
Organic Chemicals
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