J Korean Neurosurg Soc.  2005 Apr;37(4):296-299.

Primary Central Nervous System Lymphoma in Organ Recipient

• Hong KS
• Kim SD
• Lim DJ
• Park JY

Abstract

We report a case of primary central nervous system(CNS) lymphoma in an organ recipient. A 33-years-old man who underwent a renal transplantation 3years previously presented with headache and vomiting. In Brain computed tomography scans and magnetic resonance images showed multiple periventricular cystic rim enhancing masses. Pathologic diagnosis by stereotactic biopsy revealed malignant non-Hodgkins B-cell lymphoma. After pathologic confirmation, methotrexate chemotherapy and whole brain radiation therapy were done. Having experienced such a case, the authors strongly recommend to add primary CNS lymphoma as one of the differential diagnoses to brain abscess, metastatic brain tumor and glioblastoma multiforme in cases of multiple ring enhancing periventricular lesions of immunocompromised patient or organ recipient.

Keyword

Primary central nervous system lymphoma; Organ recipient; Periventricular lesion; Ring enhancement

MeSH Terms

Biopsy
Brain
Brain Abscess
Brain Neoplasms
Central Nervous System*
Diagnosis
Diagnosis, Differential
Drug Therapy
Glioblastoma
Headache
Immunocompromised Host
Kidney Transplantation
Lymphoma*
Lymphoma, B-Cell
Methotrexate
Vomiting
Methotrexate