J Korean Neurol Assoc.
2003 Apr;21(2):195-198.
A Case of Extrapontine Myelinolysis with both Frontal Lobe Dysfunction and Decreased Perfusion in SPECT
- Affiliations
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- 1Department of Neurology, Wonkwang University School of Medicine, 344-2 Sinyong-dong, Iksan-si, Jeonbuk-do, 570-180, Korea. yosik@wonkwang.ac.kr
- 2Department of Internal Medicine, Wonkwang University School of Medicine, Korea.
Abstract
- A thirty-nine year old woman was consulted because of personality change, agitation and memory disturbance. She received chemotherapy and oral steroids because of carcinoma within the bronchus. She had a high serum osmolarity caused by hyperglycemia and hypernatremia, and it was corrected rapidly. Her brain MRI showed EPM (extrapontine myelinolysis). Brain SPECT showed hypoperfusion in the bilateral orbitofrontal regions. We report a patient with EPM with typical frontal lobe dysfunction as an initial manifestation and bilateral orbitofrontal hypoperfusion.
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