J Korean Neurol Assoc.  2007 May;25(2):218-221.

Neuropsychological Findings of Extrapontine Myelinolysis without Central Pontine Myelinolysis: Initial and Follow-up Evaluation

• Seok JI
• Lee DK
• Kang MG
• Park JH
• Kim KJ

Abstract

Central pontine myelinolysis (CPM) and extrapontine myelinolysis (EPM) are well recognized syndromes related to the rapid correction of hyponatremia. Cognitive dysfunction and neuropsychological findings, however, have seldom been reported. We present a case of EPM without CPM and report the neuropsychological findings. Neuropsychological testing showed severe impairment of attention, verbal and visual memory, visuospatial functioning, and frontal/executive functioning. Language and language-related functions were normal except for naming. Follow-up neuropsychological testing at 4 months later showed slightly less impairment than the first assessment.

Keyword

Extrapontine myelinolysis; Neuropsychological; Central pontine myelinolysis

MeSH Terms

Follow-Up Studies*
Hyponatremia
Memory
Myelinolysis, Central Pontine*
Neuropsychological Tests