J Korean Med Assoc.  2003 Jul;46(7):612-619.

Diagnosis and Treatment of Irritable Bowel Syndrome

Affiliations
  • 1Department of General Surgery, The Catholic University of Korea, College of Medicine, Kangnam St. Mary's Hospital, Korea. choim@catholic.ac.kr

Abstract

Irritable bowel syndrome (IBS) is a common chronic, relapsing functional bowel disorder. IBS can be diagnosed according to the established series of criteria excluding organic diseases, and by institution of a therapeutic trial. Treatment should be tailored to individual patients' needs and fears. Education and reassuring the patients is a simple and effective form of therapy. Correction of precipitating factors can also be therapeutic. Some patients may be helped by changing the diet, avoiding certain drugs, and reducing life stressors. Symptomatic treatment includes fiber for constipation, loperamide for diarrhea, and low-dose antidepressants or antispasmodics for pain; therapeutic efficacy of novel modalities including drugs acting on serotonin receptors are under investigation.

Keyword

Irritable bowel syndrome

MeSH Terms

Antidepressive Agents
Constipation
Diagnosis*
Diarrhea
Diet
Education
Humans
Irritable Bowel Syndrome*
Loperamide
Parasympatholytics
Precipitating Factors
Receptors, Serotonin
Antidepressive Agents
Loperamide
Parasympatholytics
Receptors, Serotonin

Figure

  • Figure 1

  • Figure 2


Reference

2. Drossman DA, Corraziari E, Talley NJ, Thomson WG, Whitehead WE, editors. The functional gastrointestinal disorders. 2000. 2nd ed. McLean: Degnon Associates.
3. Camilleri M, Choi MG. Irritable Bowel Syndrome. Aliment Pharmacol Ther. 1997. 11:3–15.
4. Drossman DA, Camilleri M, Mayer EA, Whitehead WE. AGA technical review on irritable bowel syndrome. Gastroenterology. 2002. 123:2108–2131.
Article
5. Ritchie J. Pain from distension of the pelvic colon by inflating a balloon in the irritable colon syndrome. Gut. 1973. 14:125–132.
Article
6. Almy TP, Tulin M. Alterations in man under stress. Experimental production of changes simulating the 'irritable colon'. Gastroenterology. 1947. 8:616–626.
8. Poynard T, Regimbeau C, Benhamou Y. Meta-analysis of smooth muscle relaxants in the treatment of irritable bowel syndrome. Aliment Pharmacol Ther. 2001. 15:355–361.
Article
10. Jailwala J, Imperiale TF, Kroenke K. Pharmacologic treatment of the irritable bowel syndrome : a systematic review of randomized, controlled trials. Ann Intern Med. 2000. 133:136–147.
Article
11. Jackson JL, O'Malley PG, Tomkins G, Balden E, Santoro J, Kroenke K. Treatment of functional gastrointestinal disorders with antidepressant medications : a meta-analysis. Am J Med. 2000. 108:65–72.
Article
Full Text Links
  • JKMA
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2024 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr