J Korean Neuropsychiatr Assoc.
1999 Mar;38(2):419-423.
Symptom Aggravation in an Elderly Schizophrenic due to Lorazepam Discontinuation of Long-term Use of Minimal Dosage: A Case Report
- Affiliations
-
- 1Department of Neuropsychiatry, College of Medicine & The Metnal Health Research Institute, Hanyang University, Seoul, Korea.
- 2Seoul National Mental Hospital, Seoul, Korea.
Abstract
- Withdrawal psychosis following long-term administration of benzodiazepine is relatively unclear and has rarely reported. Especially, there are few reports of lorazepam withdrawal characterized by psychotic aggravation in schizophrenia. We report a 64 years old chronic schizophreinc case who developed symptom aggravation and paroxysmal attack of severe psychotic symptom, following discontinuation of 1mg lorazepam, which has been used in combination with 100mg chlorpromazine for 13 years. It was suggested that long-term combination therapy with benzodiazepines in schizophrenia was strongly discouraged even if its dosage is minimal.
- Full Text Links
-
- Actions
-
Cited
- CITED
-
- Close
- Share
-
- Similar articles
-
- Risperdal Sachet and Oral Lorazepam versus Intramuscular Haloperidol and Lorazepam Injection for Acute Psychotic Symptom in the Elderly Patients with Organic Mental Disorder
- Treatment Experiences of High Dose Lorazepam Dependence: Two Case Reports
- Impact of High Dose Lorazepam on Seizure Threshold in Catatonia: Experience from a Case Study
- Bone Density in Chronic Schizophrenia with Long-Term Antipsychotic Treatment: Preliminary Study
- Case study of a long-term care resident with oral health problem
