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Investigation of the Relationship Between Cognitive Functions and Retinal Findings From Spectral Optical Coherence Tomography in Patients With Schizophrenia and Their Healthy Siblings

Tas¸ delen R, Ayık B, Kaya H, Sevimli N

Objective Retinal structural changes which were investigated by optical coherence tomography (OCT) have been reported in schizophrenia. Since cognitive dysfunction is a core feature of schizophrenia, the correlations between retinal...
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Family Based Genome-Wide Association Analysis of Schizophrenia in a Korean Population: A Pilot Study

Bae SJ, Lee BD, Park JM, Lee YM, Moon E, Jeong HJ, Suh H, Kim K, Oh HY

Objectives: Schizophrenia (SPR) is the most devastating mental illness that causes severe deterioration in social and occupational functioning, but, the aetiology remains unknown. The aim was to identify patterns of...
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Cariprazine — an Alternative Treatment for Clozapine-resistant Schizophrenia?

Montgomery A, Rogowska M, Dratcu L

Treatment-resistant schizophrenia (TRS) poses a significant therapeutic challenge in psychiatric practice. Clozapine is recognized as a treatment of choice in TRS but is not always effective in alleviating patients’ symptoms....
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Efficacy of Asenapine in Drug-resistant Psychotic Patients with Dopamine Supersensitivity Psychosis: Two Cases

Kanahara N, Kimura H, Kinoshita T, Iyo M, Takekita Y

Dopamine supersensitivity psychosis (DSP) is an unstable clinical condition observed in individuals with schizophrenia who have been treated with an antipsychotic medication at a high dosage and/or for a long...
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Evaluation Expression of the Caspase-3 and Caspase-9 Apoptotic Genes in Schizophrenia Patients

Dirican E, Özcan H, Uzunçakmak SK, Takım U

Objective: Apoptosis is programmed cell death that occurs by several pathways. Caspase-3 is induced by active caspase-9 via the intrinsic pathway. The aim of this research was to explore the...
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Relation of ATPase6 Mutations and Telomere Length in Schizophrenia Patients

Uzuncakmak SK, Dirican E, Ozcan H, Takim U

Objective: Schizophrenia is a serious mental disorder. Mutations in mitochondrial genes can change energy metabolism. Telomere is a tandem sequence at the end of chromosomes. Shorter telomere length has been...
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Effects of Long-acting Injectable 3-Monthly Paliperidone Palmitate on the Clinical and Social Performance of Patients with Schizophrenia

Oh J, Oh J, Kim DW, Youn H, Kim SH, Kim SI, Chung IW, Wang KS, Kim M, Paik JW, Koh MJ, Lee Y, Choi SY, Kim JJ

Objective: To investigate the effects of long-acting injectable 3-monthly paliperidone palmitate on the clinical and social functioning of patients with schizophrenia. Methods: This study enrolled patients with schizophrenia receiving long-acting injectable...
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Effects of Dietary Habits on General and Abdominal Obesity in Community-dwelling Patients with Schizophrenia

Kim M, Yang SJ, Kim HH, Jo A, Jhon M, Lee JY, Ryu SH, Kim JM, Kweon YR, Kim SW

Objective: To investigate the effects of dietary habits on general and abdominal obesity in community-dwelling patients with schizophrenia spectrum disorder according to sex. Methods: A total of 270 patients with schizophrenia...
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Effectiveness of Switching to Long-acting Injectable Aripiprazole in Patients with Recent-onset and Chronic Schizophrenia

Kim SW, Lee BJ, Cheon EJ, Won SH, Jo A, Kim JM, Chung YC

Objective: This study investigated the effectiveness of switching to once-monthly long-acting injectable (LAI) aripiprazole from other second-generation antipsychotics including LAI paliperidone palmitate in both recent-onset and chronic schizophrenia patients. Methods: This...
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Computerized Version of the Kiddie Schedule for Affective Disorders and Schizophrenia for School-Age Children (KSADS-COMP): Development and Validation of the Korean Clinician-Administered Version

Lee J, Kim SJ, Kim D, Yang SJ, Lee S, Lee A, Shin Y

Objective The purpose of the present study was to develop and validate the Korean version of the clinician-administered KSADSCOMP, which is the recently updated, web-based computerized version of the Kiddie...
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Sexuality and Quality of Life in Eastern Taiwan People With Schizophrenia

Chung MH, Chao JK, Ma MC, Lin RW

Objective Patients with schizophrenia are living at the border of society and their sexuality is often neglected. The aim of the study is to explore the association among The Brief...
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The Effect of Second-Generation Antipsychotics Administration for 1-Year on the Platelet Activities in Patients With Schizophrenia: Retrospective Study

Oh YS, Lee JW, Oh HS, Kim SJ, Im WY, Lee NH, Kim JW

Objectives:This study was conducted to investigate the effect of 1-year administration of second-generation antipsychotics (SGAs) on the platelet activity in patients with schizophrenia through a retrospective review of the medical...
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Development and Effectiveness of Emotional Intelligence Promotion Program for Schizophrenia

Jung MY, Bae J

Purpose: The emotional problem of schizophrenia is an important factor that directly affects interpersonal relations and social behavior and can put them at risk of worsening symptoms and recurrence. This...
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Changes in People with Schizophrenia during the COVID-19 Pandemic: An Integrative Review

Kang KI, Choi DJ, Joung J

Purpose: This integrative review aims to identify changes in people with schizophrenia during the COVID-19 pandemic. Methods: An integrative literature review method of Whittemore and Knafl was applied to integrate the...
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Triple-Network Dysconnectivity in Patients With First-Episode Psychosis and Individuals at Clinical High Risk for Psychosis

Kim A, Ha M, Kim T, Park S, Lho SK, Moon SY, Kim M, Kwon JS

Objective In the triple-network model, the salience network (SN) plays a crucial role in switching between the default-mode network (DMN) and the central executive network (CEN). Aberrant patterns of triple-network...
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The Effect of TNF-alpha rs1800629 Polymorphism on White Matter Structures and Memory Function in Patients With Schizophrenia: A Pilot Study

Kang N, Shin W, Jung S, Bang M, Lee SH

Objective This study investigated the effect of TNF-α rs1800629 polymorphism on white matter integrity and memory function in patients with schizophrenia. Methods Fifty-five participants with schizophrenia were enrolled in this study....
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Psychometric Properties of the Mental Health Continuum-Short Form (MHC-SF): A Study With Individuals With Schizophrenia Living in the Community

Lim YJ

Objective The Mental Health Continuum-Short Form (MHC-SF) is widely used to measure positive mental health. This study is the first to examine the psychometric properties of the MHC-SF in persons...
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Deconstructing Mechanisms of Abnormal Categorical Perception of Emotional Facial Expressions in Schizophrenia Patients

Zhang J, Wang R, Xue Y

Objective The current study aims to find out the potential reasons why most schizophrenia patients have a relatively low sensitivity to the classification of emotional facial expressions. Methods By using an...
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Systematic Review and Meta-Analysis of Damage Associated Molecular Patterns HMGB1 and S100B in Schizophrenia

Mackey M, Holleran L, Donohoe G, McKernan DP

Objective Immune system dysregulation is hypothesised to be central to the aetiopathogenesis of schizophrenia; however, the role of sterile inflammation remains unclear. Damage associated molecular patterns are key initiators of...
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Combating with Compassion Fatigue: The Perspective of Family Caregivers of People with Schizophrenia

Upasen R, Saengpanya W

Purpose: The purpose of this study was to explore the coping processes used by family caregivers of individuals with schizophrenia to deal with compassion fatigue (CF). Methods: Grounded theory was used...
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