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A Case of Clozapine-induced Corneal and Lenticular Pigmentation

An JS, Lee YM, Kwag JY, Hyun J, Choi JS, Pak KH, Chung SK

PURPOSE: To report a case of corneal and lenticular pigmentation after prolonged clozapine therapy. CASE SUMMARY: A 56-year-old male visited our hospital with a progressive decline in vision that affected both...
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Benzodiazepine-Associated Carcinogenesis: Focus on Lorazepam-Associated Cancer Biomarker Changes in Overweight Individuals

Ku SC, Ho PS, Tseng YT, Yeh TC, Cheng SL, Liang CS

OBJECTIVE: Cellular, animal, and human epidemiological studies suggested that benzodiazepines increase the risk of cancer and cancer mortality. Obesity is also clearly linked to carcinogenesis. However, no human studies have...
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Negative myoclonus associated with pregabalin

Park KD, Kim MK, Lee SJ

Negative myoclonus (NM) is a jerky, shock-like involuntary movement caused by a sudden, brief interruption of muscle contraction. An 80-year-old man presented with multifocal NM and confusion. Two days before...
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Impact of High Dose Lorazepam on Seizure Threshold in Catatonia: Experience from a Case Study

Kar SK, Kumar S, Singh A

No abstract available.
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The Efficacy and Safety of Clonazepam in Patients with Anxiety Disorder Taking Newer Antidepressants: A Multicenter Naturalistic Study

Wang SM, Kim JB, Sakong JK, Suh HS, Oh KS, Woo JM, Yoo SW, Lee SM, Lee SY, Lim SW, Cho SJ, Chee IS, Chae JH, Hong JP, Lee KU

OBJECTIVE: This study compared the efficacy and tolerability of clonazepam with other benzodiazepines in patients with anxiety disorders. METHODS: Inclusion criteria were as follows: age >20 years, diagnosis of anxiety disorder...
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Low Plasma Insulin Level Prolonged Hypoglycemia after High dose Insulin Lispro Injection

Kang JH, Park HS

Increased plasma insulin levels are often observed in exogenous insulin overdose patients. However, plasma insulin level may decrease with time. We report a case of low plasma insulin level hypoglycemia...
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Anti-Intrusion Effect of Lorazepam: An Experimental Study

Lee HS, Lee HP, Lee SK, Kim YK, Choi YK

  • KMID: 2316300
  • Psychiatry Investig.
  • 2013 Sep;10(3):273-280.
OBJECTIVE: Easy triggering of trauma-related episodic memory fragments caused by perceptual cues is tied to strong perceptual priming in the implicit memory system. And among benzodiazepines, only lorazepam has been...
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Korean Addiction Treatment Guidelines Series (II): Pharmacological Treatment of Alcohol Withdrawal

Kim HY, Lee HK, Lee KS, Joe KH, Choi SW, Seo JS

  • KMID: 2342549
  • J Korean Neuropsychiatr Assoc.
  • 2013 Mar;52(2):67-75.
OBJECTIVES: In development of Korean addiction treatment guidelines, the aim of this study was to investigate the experts' consensus regarding current pharmacological practice in treatment of alcohol withdrawal. METHODS: Using recommendations...
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Opioids and the Gastrointestinal Tract: A Case of Narcotic Bowel Syndrome and Literature Review

Farmer AD, Ferdinand , Aziz Q

  • KMID: 2325978
  • J Neurogastroenterol Motil.
  • 2013 Jan;19(1):94-98.
The worldwide use of opiates is increasing yet there is little evidence that in long-term, non-cancer patients, they have an efficacious effect on functional outcomes and quality of life measures....
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Detection of Human Herpesvirus-6 (HHV-6) in Cerebrospinal Fluid of a Patient with Fatal Status Epilepticus

Cho SM, Song JS, Kang EK

  • KMID: 2059501
  • J Korean Child Neurol Soc.
  • 2012 Sep;20(3):196-200.
Human herpesvirus-6 (HHV-6) often causes mild illnesses, but is rarely associated with encephalitis or other fatal neurological conditions. We report a girl who died of a intractable status epilepticus from...
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Dexmedetomidine sedation in ICU

Yu SB

Dexmedetomidine (DEX), a highly selective alpha2-adrenergic receptor agonist, is the newest agent introduced for sedation in intensive care unit (ICU). The sedation strategy for critically ill patients has stressed light...
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Clinical Characteristics and Use of Antidepressants among Cancer Patients Referred for Psychiatric Consultation : A Korean Multicenter Survey

Park JS, Ha J, Lim S, Kim TS, Ha JH, Paik JW, Lee BC, Choe BM, Lee KJ, Kim SW, Yang JC, Ko YH, Oh KS

  • KMID: 2342421
  • J Korean Neuropsychiatr Assoc.
  • 2012 Nov;51(6):387-394.
OBJECTIVES: Antidepressants are frequently used for treatment of psychological distress among cancer patients. The aim of this study is to investigate the characteristics of psychiatric consultations and antidepressant use for...
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A Case of Transient Psychosis after Sustained Release Bupropion Overdose

Na KS, Lee SI, Jung HY

  • KMID: 2287494
  • Korean J Psychopharmacol.
  • 2011 Jul;22(3):161-165.
Bupropion is a unique antidepressant with enhancing both noradrenergic and dopaminergic neurotransmission without altering serotonergic system. Given its pharmacodynamics and structural similarity to amphetamine, the possibility of bupropionrelated psychosis has...
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Unexpected Seizure Attack in a Patient with Spinal Metastasis Diagnosed as Posterior Reversible Encephalopathy Syndrome

Kim CH, Kim CH, Chung CK, Jahng TA

Seizure is a foreseeable risk in patients with brain lesion. However, seizure during treating non-brain lesion is not a familiar situation to neurosurgeon. Posterior reversible encephalopathy syndrome (PRES) is a...
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Use of Lorazepam in Drug-Assisted Interviews: Two Cases of Dissociative Amnesia

Lee SS, Park S, Park SS

  • KMID: 2316152
  • Psychiatry Investig.
  • 2011 Dec;8(4):377-380.
Drug-assisted interviews are useful for psychiatric diagnosis and treatment. However, amobarbital, a typical medication used for this purpose, is associated with elevated risk of respiratory depression. Benzodiazepines are good substitutes...
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Persistent Seizure after Propofol-Induced General Anesthesia in Recovery Room: A Case Report

Kim B, Chung S

There are a few case reports describing persistent seizure following propofol. A 45-year-old female underwent operation of mastoidectomy and tympanoplasty. She had no personal or family history of epilepsy. Anesthesia...
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Korean Medication Algorithm Project for Generalized Anxiety Disorder 2009 (I) : Initial Treatment Strategy

Kim MS, Yu BH, Kim CH, Yang JC, Lee SH, Lee JY, Suh HS, Study Group for Korean Medication Algorithm Project for Generalized Anxiety Disorder 2009

  • KMID: 2341820
  • J Korean Neuropsychiatr Assoc.
  • 2010 Nov;49(6):546-552.
OBJECTIVES: This study investigated the consensus about treatment strategies for the initial treatment of generalized anxiety disorder (GAD). This issue represents one of the subjects addressed by the Korean Medication...
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A Case of Cyclic Vomiting Syndrome Responding to Gonadotropin-Releasing Hormone Analogue

Shin YK, Kwon JG, Kim KY, Park JB, Han SJ, Cheon JW, Kim EY, Kim HG, Lee TS, Park KS, Won KS

  • KMID: 2326121
  • J Neurogastroenterol Motil.
  • 2010 Jan;16(1):77-82.
Cyclic vomiting syndrome (CVS) is a disorder characterized by recurrent episodes of incapacitating nausea and vomiting interspersed with symptom free periods. Common triggers of cyclic vomiting include noxious stress, excitement,...
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Pharmacotherapy of Generalized Anxiety Disorder and Pregabalin

Jung YE, Chae JH

  • KMID: 2287425
  • Korean J Psychopharmacol.
  • 2008 May;19(3):136-146.
Multiple randomized, double-blind, placebo-controlled trials have explored the efficacy of pregabalin for the treatment of generalized anxiety disorder (GAD) and this novel drug was recently approved in Europe. Short-term efficacy...
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Comparison of Clinical Outcomes and Treatment Methods Applying International Guideline in Status Epilepticus

Kim HS, Kim SK, Hwang IT, Lee KH

  • KMID: 2059402
  • J Korean Child Neurol Soc.
  • 2008 May;16(1):28-35.
PURPOSE: Status epilepticus(SE) is a common neurological emergency in childhood. SE is defined as a seizure or series of seizures without recovery of consciousness between seizures lasting at least 30...
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