J Korean Neurol Assoc.  1983 Dec;1(2):10-16.

Effect of Lorazepam injection on Status Epilepticus

Affiliations
  • 1Department of Neurology, Seoul National University.

Abstract

Status epilepticus is a neurological emergency requiring immediate effective care to avoid permanent brain damage or death. There is no single ideal pharmacological agent that can be used for status epilepticus. The author has studied the effect of intravenous lorazepam in the tratment of status epilepticus occurring in eighteen patients. Lorazepam controlled status epilepticus in sixteen (88%) of the eighteen patents, showed no side effect such as depressant action on respiratory and cardiovascular system. Also it seemed that lorazepam acted rapidly and its effect lasted at least for over eight hours. Except a few cases who had had prolonged hangover, the injection seemed to be handy and safe treatment without requiring EKG monitoring and repeated electrolyte check etc. as in dilantinization.


MeSH Terms

Brain
Cardiovascular System
Electrocardiography
Emergencies
Humans
Lorazepam*
Phenytoin
Status Epilepticus*
Lorazepam
Phenytoin
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