J Korean Pain Soc.  2001 Jun;14(1):114-117.

Clinical Experience of Prolotherapy for Chronic Musculoskeletal Disease: A report of 5 cases

• Lee CW
• Kim YS
• Ahn JK
• Song BH
• Jung DS
• Hwang HE

Abstract

A significant injury of ligament or tendon that might result in hypermobility and/or instability has been termed connective tissue insufficiency (CTI). Load bearing on CTI can sometimes create a malfunction of the mechanoreceptor and this in turn can aggravate the problem thus creating a chronic condition. Prolotherapy means the injection of growth factors or growth factor stimulators into the fibroosseous junction of the disabled ligament, tendon or cartilages in order to strengthen and promote proliferation of the injured Connective tissue. In the case of frequent recurrence or unresponsiveness to conservative treatment including nerve blocks in the chronic musculoskeletal disorder. We obtained good results after the prolotherapy treatment. This study will report on 5 cases of prolotherapy treatment.

Keyword

Connective tissue insufficiency; Musculoskeletal disease; Prolotherapy

MeSH Terms

Cartilage
Connective Tissue
Intercellular Signaling Peptides and Proteins
Ligaments
Mechanoreceptors
Musculoskeletal Diseases*
Nerve Block
Recurrence
Tendons
Weight-Bearing
Intercellular Signaling Peptides and Proteins