- Human platelet lysate efficiency, stability, and optimal heparin concentration required in culture of mammalian cells
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Mohamed HE, Asker ME, Kotb NS, El Habab A
- KMID: 2472006
- Blood Res.
- 2020 Mar;55(1):35-43.
- doi: 10.5045/br.2020.55.1.35
BACKGROUND: Fetal bovine serum (FBS) has been used to support the growth and proliferation of mammalian cells for decades. Owing to several risk factors associated with FBS, several trials have... -
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- Proteomic Classification and Identification of Proteins Related to Tissue Healing of Platelet-Rich Plasma
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Lee HW, Choi KH, Kim JY, Kim KO, Haotian B, Yuxuan L, Noh KC
- KMID: 2470060
- Clin Orthop Surg.
- 2020 Mar;12(1):120-129.
- doi: 10.4055/cios.2020.12.1.120
BACKGROUND: Platelet-rich plasma (PRP) is a plasma component of autologous blood containing a high concentration of platelets. PRP is used to promote healing of damaged tissues. However, there are not... -
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- Therapeutic Angiogenesis with Somatic Stem Cell Transplantation
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Murohara T
- KMID: 2465659
- Korean Circ J.
- 2020 Jan;50(1):12-21.
- doi: 10.4070/kcj.2019.0288
Therapeutic angiogenesis is an important strategy to rescue ischemic tissues in patients with critical limb ischemia having no other treatment option such as endovascular angioplasty or bypass surgery. Studies indicated... -
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- A Case of Surgical Treatment of Intractable Vocal Fold Scar Using Basic Fibroblast Growth Factor and Collagen Scaffold
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Kang HT, Kim HJ, Park KN, Lee SW
- KMID: 2470496
- J Korean Soc Laryngol Phoniatr Logoped.
- 2019 Dec;30(2):124-127.
- doi: 10.22469/jkslp.2019.30.2.124
Vocal fold scarring is an intractable phonosurgical condition. The number of patients with vocal fold scars is increasing with the aging of society and with the increasing application of laryngeal... -
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- Wound Healing Potential of Low Temperature Plasma in Human Primary Epidermal Keratinocytes
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Cui HS, Cho YS, Joo SY, Mun CH, Seo CH, Kim JB
- KMID: 2467051
- Tissue Eng Regen Med.
- 2019 Dec;16(6):585-593.
- doi: 10.1007/s13770-019-00215-w
BACKGROUND: Low temperature plasma (LTP) was recently shown to be potentially useful for biomedical applications such as bleeding cessation, cancer treatment, and wound healing, among others. Keratinocytes are a major... -
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- Platelet-rich fibrin along with a modified minimally invasive surgical technique for the treatment of intrabony defects: a randomized clinical trial
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Ahmad N, Tewari S, Narula SC, Sharma RK, Tanwar N
- KMID: 2465380
- J Periodontal Implant Sci.
- 2019 Dec;49(6):355-365.
- doi: 10.5051/jpis.2019.49.6.355
PURPOSE: The modified minimally invasive surgical technique (M-MIST) has been successfully employed to achieve periodontal regeneration. Platelet-rich fibrin (PRF) is known to enhance wound healing through the release of growth... -
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- Reduction in post extraction waiting period for dental implant patients using plasma rich in growth factors: an in vivo study using cone-beam computed tomography
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Arya V, Malhotra V, Rao JD, Kirti S, Malhotra S, Sharma RS
- KMID: 2461481
- J Korean Assoc Oral Maxillofac Surg.
- 2019 Oct;45(5):285-293.
- doi: 10.5125/jkaoms.2019.45.5.285
OBJECTIVES: This study examined the effects of plasma-rich growth factors (PRGF) on accelerating bone regeneration/repair in fresh extraction sockets, and determined the quality and quantity of bone by assessing the... -
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- Melandrium firmum Extract Promotes Hair Growth by Modulating 5α-Reductase Activity and Gene Expression in C57BL/6J Mice
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Huang B, Kang BG, Lim SS, Zhang XH
- KMID: 2456226
- Ann Dermatol.
- 2019 Oct;31(5):502-510.
- doi: 10.5021/ad.2019.31.5.502
BACKGROUND: In our preliminary study, we screened for their potential to inhibit 5α-reductase, and Melandrium firmum (MF) extract showed the most potent activity as confirmed by high-performance liquid chromatography (HPLC). OBJECTIVE:... -
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- Mechanical and Mechanosensing Properties of Tumor Affected Bone Cells Were Inhibited via PI3K/Akt Pathway
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Lee T
- KMID: 2457437
- J Bone Metab.
- 2019 Aug;26(3):179-191.
- doi: 10.11005/jbm.2019.26.3.179
BACKGROUND: Osteolytic metastasis is a common destructive form of metastasis, in which there is an increased bone resorption but impaired bone formation. It is hypothesized that the changed mechanical properties... -
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- Preparation and Characterization of Human Adipose Tissue-Derived Extracellular Matrix, Growth Factors, and Stem Cells: A Concise Review
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Chun SY, Lim JO, Lee EH, Han MH, Ha YS, Lee JN, Kim BS, Park MJ, Yeo M, Jung B, Kwon TG
- KMID: 2455047
- Tissue Eng Regen Med.
- 2019 Aug;16(4):385-393.
- doi: 10.1007/s13770-019-00199-7
BACKGROUND: Human adipose tissue is routinely discarded as medical waste. However, this tissue may have valuable clinical applications since methods have been devised to effectively isolate adipose-derived extracellular matrix (ECM),... -
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- Udenafil Induces the Hair Growth Effect of Adipose-Derived Stem Cells
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Choi N, Sung JH
- KMID: 2455096
- Biomol Ther.
- 2019 Jul;27(4):404-413.
- doi: 10.4062/biomolther.2018.195
Udenafil, which is a PDE5 inhibitor, is used to treat erectile dysfunction. However, it is unclear whether udenafil induces hair growth via the stimulation of adipose-derived stem cells (ASCs). In... -
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- Role of proteases, cytokines, and growth factors in bone invasion by oral squamous cell carcinoma
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Son SH, Chung WY
- KMID: 2452745
- Int J Oral Biol.
- 2019 Jun;44(2):37-42.
- doi: 10.11620/IJOB.2019.44.2.37
Oral squamous cell carcinoma (OSCC) is the most common oral malignancy and an increasing global public health problem. OSCC frequently invades the jaw bone. OSCC-induced bone invasion has a significant... -
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- Mechanistic Target of Rapamycin Pathway in Epileptic Disorders
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Kim JK, Lee JH
- KMID: 2453232
- J Korean Neurosurg Soc.
- 2019 May;62(3):272-287.
- doi: 10.3340/jkns.2019.0027
The mechanistic target of rapamycin (mTOR) pathway coordinates the metabolic activity of eukaryotic cells through environmental signals, including nutrients, energy, growth factors, and oxygen. In the nervous system, the mTOR... -
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- Synthesized Ceramide Induces Growth of Dermal Papilla Cells with Potential Contribution to Hair Growth
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Oh JH, Jeong KH, Kim JE, Kang H
- KMID: 2439062
- Ann Dermatol.
- 2019 Apr;31(2):164-174.
- doi: 10.5021/ad.2019.31.2.164
BACKGROUND: The ceramide is known to play an important role in the formation of intracellular lipids, and play a crucial role as a barrier for skin and hair cuticle. Recent... -
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- Adipose-Derived Stem Cell Coculturing Stimulates Integrin-Mediated Extracellular Matrix Adhesion of Melanocytes by Upregulating Growth Factors
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Kim H, Yi N, Do BR, Lee AY
- KMID: 2442010
- Biomol Ther.
- 2019 Feb;27(2):185-192.
- doi: 10.4062/biomolther.2018.203
Coculture with adipose-derived stem cells (ADSCs) can stimulate proliferation and migration of melanocytes. To enhance outcomes of skin disorders caused by melanocyte loss or death, mixed transplantation with ADSCs has... -
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- Effect of bFGF and fibroblasts combined with hyaluronic acid-based hydrogels on soft tissue augmentation: an experimental study in rats
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Lee SY, Park Y, Hwang SJ
- KMID: 2468994
- Maxillofac Plast Reconstr Surg.
- 2019 ;41(1):47.
- doi: 10.1186/s40902-019-0234-0
BACKGROUND: Hyaluronic acid (HA) has been applied as a primary biomaterial for temporary soft tissue augmentation and as a carrier for cells and the delivery of growth factors to promote... -
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- Autophagy Is a Potential Target for Enhancing the Anti-Angiogenic Effect of Mebendazole in Endothelial Cells
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Sung SJ, Kim HK, Hong YK, Joe YA
- KMID: 2432075
- Biomol Ther.
- 2019 Jan;27(1):117-125.
- doi: 10.4062/biomolther.2018.222
Mebendazole (MBZ), a microtubule depolymerizing drug commonly used for the treatment of helminthic infections, has recently been noted as a repositioning candidate for angiogenesis inhibition and cancer therapy. However, the... -
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- Glucosamine Hydrochloride and N-Acetylglucosamine Influence the Response of Bovine Chondrocytes to TGF-β3 and IGF in Monolayer and Three-Dimensional Tissue Culture
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Pizzolatti ALA, Gaudig F, Seitz D, Roesler CR, Salmoria G
- KMID: 2441269
- Tissue Eng Regen Med.
- 2018 Dec;15(6):781-791.
- doi: 10.1007/s13770-018-0150-x
BACKGROUND: Glucosamine hydrochloride (GlcN·HCl) has been shown to inhibit cell growth and matrix synthesis, but not with N-acetyl-glucosamine (GlcNAc) supplementation. This effect might be related to an inhibition of critical... -
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- Wound healing effects of paste type acellular dermal matrix subcutaneous injection
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Lee JH, Kim JW, Lee JH, Chung KJ, Kim TG, Kim YH, Kim KJ
- KMID: 2427539
- Arch Plast Surg.
- 2018 Nov;45(6):504-511.
- doi: 10.5999/aps.2018.00948
BACKGROUND: Acellular dermal matrix (ADM) helps wound healing by stimulating angiogenesis, acting as a chemoattractant for endothelial cells, providing growth factors, and permitting a substrate for fibroblasts to attach. The... -
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- Bioactive Compounds for the Treatment of Renal Disease
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Cho KS, Ko IK, Yoo JJ
- KMID: 2422485
- Yonsei Med J.
- 2018 Nov;59(9):1015-1025.
- doi: 10.3349/ymj.2018.59.9.1015
Kidney diseases including acute kidney injury and chronic kidney disease are among the largest health issues worldwide. Dialysis and kidney transplantation can replace a significant portion of renal function, however... -
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