Korean J Med.
2008 Dec;75(6):646-650.
Diabetic Nephropathy: New insights into the pathogenesis
- Affiliations
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- 1Department of Internal Medicine, Soonchunhyang University Medical College, Cheonan, Korea.
- 2Department of Internal Medicine, Yonsei University Wonju College of Medicine, Wonju, Korea.
Abstract
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Diabetic nephropathy is the most serious complication of diabetes mellitus and the most common cause of end-stage renal disease. It can be possible to dissect the exact mechanism of development and progression of diabetic nephropathy because the new biomedical tools for studying disease have been developed. This review explores the new insights into the pathogenesis of diabetic nephropathy, focusing the newly recognized pathways which include growth factors and inflammatory cytokines.