J Korean Pediatr Soc.
2002 Jul;45(7):912-916.
A Successful Transplant of HLA-3 Loci Mismatched Umbilical Cord Blood into a Patient with Acute Myeloid Leukemia from an Unrelated Donor
- Affiliations
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- 1Department of Pediatrics, College of Medicine, Yonsei University, Seoul, Korea. cj@yumc.yonsei.ac.kr
- 2Department of Clinical Pathology, College of Medicine, Yonsei University, Seoul, Korea.
Abstract
- Cord blood is a useful source of allogeneic hematopoietic stem cells for bone marrow reconstitution. The number of umbilical cord blood transplants is increasing worldwide. In this a case 15- month-old boy with acute myeloid leukemia was treated with umbilical cord blood transplant from an HLA-3 loci mismatched unrelated donor. Granulocyte recovery greater than 500/mm3 occurred at day 49, and the platelet recovered greater than 20,000/mm3 independent of transfusion at day 81 after stem cell infusion.
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