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Identification of MicroRNA Related to the CD34+ Cell Fraction of Cord Blood Stem Cells

Lee JH, Song EY, Kim N, Roh EY, Park HW, Yoon JH, Shin S

BACKGROUND: Cord blood (CB) is a reliable source of hematopoietic stem cells, and its utilization in stem cell transplantation is increasing continuously. The CD34+ cell count is arguably one of...
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Prenatal Secondhand Smoke Exposure: Correlation Between Nicotine in Umbilical Cord Blood and Neonatal Anthropometry

Ramadani M, Utomo B, Achadi EL, Gunardi H

OBJECTIVES: Nicotine narrows uterine blood vessels reducing the flow of oxygen and nutrients to the developing fetus. This study examined the effects of fetal exposure to secondhand smoke on neonatal...
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Efficacy of a Hair Tonic Containing Human Umbilical Cord Blood Mesenchymal Stem Cell-derived Conditioned Media in Patients with Androgenetic Alopecia

Han HS, Park KY, Ko EJ, Kim BJ

  • KMID: 2451586
  • Korean J Dermatol.
  • 2019 Jun;57(5):251-257.
BACKGROUND: The development of a safe and convenient agent that can promote hair growth in patients with androgenetic alopecia remains challenging. OBJECTIVE: This study was designed to investigate the efficacy of...
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Effect of Maternal Depression on Brain-derived Neurotrophic Factor Levels in Fetal Cord Blood

Sonmez EO, Uguz F, Sahingoz M, Sonmez G, Kaya N, Camkurt MA, Gokmen Z, Basaran M, Gezginc K, Erdem SS, Dulger HH, Tasyurek E

OBJECTIVE: We aimed to assess the association between cord blood brain-derived neurotrophic factor (BDNF) concentration and maternal depression during pregnancy. METHODS: A total of 48 pregnant women, admitted for elective caesarean...
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Cord blood 2.0: state of the art and future directions in transplant medicine

Wagner JE

No abstract available.
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Prenatal Exposure to Lead and Chromium is Associated with IL-13 Levels in Umbilical Cord Blood and Severity of Atopic Dermatitis: COCOA Study

Kim J, Kim S, Woo SY, Chung JY, Hong YS, Oh SY, Choi SJ, Oh SY, Kim KW, Shin YH, Won HS, Lee KJ, Kim SH, Kwon JY, Lee SH, Hong SJ, Ahn K

There have been few studies investigating the association between atopic dermatitis (AD) and prenatal exposure to heavy metals. We aimed to evaluate whether prenatal exposure to heavy metals is associated...
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Bone regeneration with umbilical cord blood mesenchymal stem cells in femoral defects of ovariectomized rats

Hong B, Lee S, Shin N, Ko Y, Kim D, Lee J, Lee W

OBJECTIVES: Current treatments for osteoporosis were prevention of progression, yet it has been questionable in the stimulation of bone growth. The mesenchymal stem cells (MSCs) treatment for osteoporosis aims to...
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Storage and use of cord blood

Lee YH

Cord blood (CB) has been used as an important source for hematopoietic stem cell transplantation and has been stored in public CB banks (CBBs) worldwide since the mid-1990s. Recently, the...
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Human umbilical cord blood mesenchymal stem cells engineered to overexpress growth factors accelerate outcomes in hair growth

Bak DH, Choi MJ, Kim SR, Lee BC, Kim JM, Jeon ES, Oh W, Lim ES, Park BC, Kim MJ, Na J, Kim BJ

Human umbilical cord blood mesenchymal stem cells (hUCB-MSCs) are used in tissue repair and regeneration; however, the mechanisms involved are not well understood. We investigated the hair growth-promoting effects of...
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Effects and Predictive Factors of Immunosuppressive Therapy Combined with Umbilical Cord Blood Infusion in Patients with Severe Aplastic Anemia

Zhang X, Li Z, Geng W, Song B, Wan C

PURPOSE: To investigate the efficacy and safety of umbilical cord blood (UCB) infusion (UCBI) plus immunosuppressive therapy (IST) treatment in comparison to IST treatment, as well as predictive factors for...
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Assessment of the Value of the Umbilical Cord Blood Gas Parameter as Indicator of the Neonatal Condition

Lee JM, Shin HB, Choi YB, Lee NM, Yi DY, Yun SW, Chae SA, Lim IS

OBJECTIVE: Umbilical cord blood gas analysis has widely been used to objectively evaluate the medical condition of newborn. Because umbilical cord blood gas analysis enables an immediate assessment of the...
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Haptoglobin Concentration in the Cord Blood of Uninfected Korean Newborns

Choi SJ, Lee B, Ahn K, Uh Y

OBJECTIVE: Highly sensitive haptoglobin measurement should be used in neonates because the haptoglobin concentration in neonates is lower than that of adults. The aim of this study was to establish...
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MiR-9 Controls Chemotactic Activity of Cord Blood CD34⁺ Cells by Repressing CXCR4 Expression

Ha TW, Kang HS, Kim TH, Kwon JH, Kim HK, Ryu A, Jeon H, Han J, Broxmeyer , Hwang Y, Lee YK, Lee MR

Improved approaches for promoting umbilical cord blood (CB) hematopoietic stem cell (HSC) homing are clinically important to enhance engraftment of CB-HSCs. Clinical transplantation of CB-HSCs is used to treat a...
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Safety of Autologous Umbilical Cord Blood Therapy for Acquired Sensorineural Hearing Loss in Children

Baumgartner LS, Moore E, Shook D, Messina S, Day MC, Green J, Nandy R, Seidman M, Baumgartner JE

BACKGROUND AND OBJECTIVES: Sensorineural hearing loss (SNHL) in children is associated with neurocognitive morbidity. The cause of SNHL is a loss of hair cells in the organ of Corti. There...
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The role of cord blood banks in the cell therapy era: future perspectives

Lee YH

No abstract available.
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Effects of cord blood vitamin D levels on the risk of neonatal sepsis in premature infants

Say B, Uras N, Sahin S, Degirmencioglu H, Oguz SS, Canpolat F

PURPOSE: Vitamin D plays a key role in immune function. Vitamin D deficiency may play a role in the pathogenesis of infections, and low levels of circulating vitamin D are...
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Evaluation of Malondialdehyde, Superoxide Dismutase and Catalase Activity in Fetal Cord Blood of Depressed Mothers

Camkurt MA, Fındıklı E, Bakacak M, Tolun FÄ, Karaaslan

OBJECTIVE: The umbilical cord consists of two arteries and one vein and it functions in the transport between the maternal and fetal circulation. Biochemical analysis of fetal cord blood (FCB)...
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Transplantation of human umbilical cord blood CD34⁺ cells into the liver of newborn NOD/SCID/IL-2Rγ null (NSG) mice after busulfan conditioning

Ko Y, Jeong YH, Lee JA

No abstract available.
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Direct Conversion of Human Umbilical Cord Blood into Induced Neural Stem Cells with SOX2 and HMGA2

Kim JJ, Shin JH, Yu KR, Lee BC, Kang I, Lee JY, Kim DH, Seo Y, Kim HS, Choi SW, Kang KS

Recent advances have shown the direct reprogramming of mouse and human fibroblasts into induced neural stem cells (iNSCs) without passing through an intermediate pluripotent state. Thus, direct reprogramming strategy possibly...
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A Simple Method to Isolate and Expand Human Umbilical Cord Derived Mesenchymal Stem Cells: Using Explant Method and Umbilical Cord Blood Serum

Hassan G, Kasem I, Soukkarieh C, Aljamali M

BACKGROUND AND OBJECTIVES: Mesenchymal stem cells (MSCs) are multipotent stem cells that can be isolated from umbilical cords and are therapeutically used because of their ability to differentiate into various...
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