- Characteristics of DNMT3A mutations in acute myeloid leukemia
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Park DJ, Kwon A, Cho BS, Kim HJ, Hwang KA, Kim M, Kim Y
- KMID: 2472004
- Blood Res.
- 2020 Mar;55(1):17-26.
- doi: 10.5045/br.2020.55.1.17
BACKGROUND: DNMT3A mutations occur in approximately 20% of AML cases and are associated with changes in DNA methylation. CDKN2B plays an important role in the regulation of hematopoietic progenitor cells... -
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- Clinical significance of T cell receptor excision circle (TREC) quantitation after allogenic HSCT
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Mikhael NL, Elsorady M
- KMID: 2466593
- Blood Res.
- 2019 Dec;54(4):274-281.
- doi: 10.5045/br.2019.54.4.274
BACKGROUND: Hematopoietic stem cell transplantation (HSCT) is a well-established treatment modality for a variety of diseases. Immune reconstitution is an important event that determines outcomes. The immune recovery of T... -
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- Adult Stem Cells: Beyond Regenerative Tool, More as a Bio-Marker in Obesity and Diabetes
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Sen S
- KMID: 2466495
- Diabetes Metab J.
- 2019 Dec;43(6):744-751.
- doi: 10.4093/dmj.2019.0175
Obesity, diabetes, and cardiovascular diseases are increasing rapidly worldwide and it is therefore important to know the effect of exercise and medications for diabetes and obesity on adult stem cells.... -
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- Lung Ultrasound to Evaluate Invasive Fungal Diseases after Allogeneic Hematopoietic Stem Cell Transplantation
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Raffaella , Lorenzo L, Elisabetta X, Andrea A, Sarah M, Fabio G, Daniela C, Maria Teresa LS, Consuelo C, Massimo B, Fabio C, Jacopo P
- KMID: 2466471
- Infect Chemother.
- 2019 Dec;51(4):386-392.
- doi: 10.3947/ic.2019.51.4.386
Invasive fungal diseases (IFDs) are a leading cause of infection-related-mortality after allogeneic hematopoietic stem cell transplantation (HSCT). In this prospective pilot study, we investigated the use of bedside lung ultrasound... -
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- Clinical Symptoms and Signs of Dry Eye Disease after Allogeneic Hematopoietic Stem Cell Transplantation
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Beak JU, Ha MJ, Yi R, Yoo YS, Kim HS, Na KS
- KMID: 2466164
- J Korean Ophthalmol Soc.
- 2019 Dec;60(12):1148-1154.
- doi: 10.3341/jkos.2019.60.12.1148
PURPOSE: To identify the symptoms and signs of patients with dry eye disease (DED) after allogenic hematopoietic stem cell transplantation (HSCT) and analyze the correlations between these signs and symptoms. METHODS:... -
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- Inactivation of the NHEJ Activity of DNA-PKcs Prevents Fanconi Anemia Pre-Leukemic HSC Expansion
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Chatla S, Wilson AF, Pang Q
- KMID: 2465886
- Int J Stem Cells.
- 2019 Nov;12(3):457-462.
- doi: 10.15283/ijsc19074
Fanconi anemia (FA) is a genetic disorder characterized by bone marrow failure and high risk of cancer particularly leukemia. Here we show that inactivation of the non-homologous end-joining (NHEJ) activity... -
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- Fluoranthene-Induced Cytotoxicity and Direct Effect of Aryl Hydrocarbon Receptor Antagonist on Hematopoietic Stem Cell Differentiation
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Yang SH, Kang MG, Kim HR, Lee YE, Na BR, Lee JH, Shin JH, Shin MG
- KMID: 2450955
- Ann Lab Med.
- 2019 Nov;39(6):580-583.
- doi: 10.3343/alm.2019.39.6.580
No abstract available. -
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- Anxiety and Depression of the Patients with Hematological Malignancies during Hospitalization for Hematopoietic Stem Cell Transplantation
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Seo HJ, Baek YG, Cho BS, Kim TS, Um YH, Chae JH
- KMID: 2462774
- Psychiatry Investig.
- 2019 Oct;16(10):751-758.
- doi: 10.30773/pi.2019.07.12
OBJECTIVE: This study aimed to assess the anxiety and depression in patients undergoing hematopoietic stem cell transplantation (HSCT). METHODS: Eighty-seven adult patients with various hematologic diseases, who were scheduled to receive... -
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- Experiences of Unrelated Hematopoietic Stem-cell Donors and Experts of Relevant Institutions
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Yu S, Kim M, Kim TG, Beom SH
- KMID: 2461067
- Korean J Adult Nurs.
- 2019 Oct;31(5):522-539.
- doi: 10.7475/kjan.2019.31.5.522
PURPOSE: This study attempts to explore the experiences of Hematopoietic Stem Cell Donation (HSCD) among donors and experts of HSCD-related institutions in South Korea. METHODS: In July 2017, 7 donors and... -
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- Clonal Cell Proliferation in Paroxysmal Nocturnal Hemoglobinuria: Evaluation of PIGA Mutations and T-cell Receptor Clonality
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Park J, Kim M, Kim Y, Han K, Chung NG, Cho B, Lee SE, Lee JW
- KMID: 2450966
- Ann Lab Med.
- 2019 Sep;39(5):438-446.
- doi: 10.3343/alm.2019.39.5.438
BACKGROUND: Paroxysmal nocturnal hemoglobinuria (PNH) is an acquired pluripotent hematopoietic stem cell disorder associated with an increase in the number of glycosyl-phosphatidyl inositol (GPI)-deficient blood cells. We investigated PNH clonal... -
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- Identification of MicroRNA Related to the CD34+ Cell Fraction of Cord Blood Stem Cells
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Lee JH, Song EY, Kim N, Roh EY, Park HW, Yoon JH, Shin S
- KMID: 2457170
- Korean J Blood Transfus.
- 2019 Aug;30(2):113-123.
- doi: 10.17945/kjbt.2019.30.2.113
BACKGROUND: Cord blood (CB) is a reliable source of hematopoietic stem cells, and its utilization in stem cell transplantation is increasing continuously. The CD34+ cell count is arguably one of... -
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- Mesenchymal Stem Cells from the Wharton's Jelly of the Human Umbilical Cord: Biological Properties and Therapeutic Potential
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Marino L, Castaldi M, Rosamilio , Ragni E, Vitolo R, Fulgione C, Castaldi S, Serio B, Bianco R, Guida M, Selleri C
- KMID: 2465893
- Int J Stem Cells.
- 2019 Jul;12(2):218-226.
- doi: 10.15283/ijsc18034
Wharton's jelly mesenchymal stem cells (WJ-MSCs) are a class of stem cells with high differentiative potential, an immuno-privileged status and easy access for collection, which raise no legal or ethical... -
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- Stem cell-based therapy for inflammatory bowel disease
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Shimizu H, Suzuki K, Watanabe M, Okamoto R
- KMID: 2454739
- Intest Res.
- 2019 Jul;17(3):311-316.
- doi: 10.5217/ir.2019.00043
Inflammatory bowel disease (IBD) is an idiopathic, multi-etiological disease characterized by inflammation and mucosal destruction of the gastrointestinal tract. Despite the remarkable advance in immunomodulating therapies, there still remains a... -
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- Comparison of quality of life and depression between hematopoietic stem cell transplantation survivors and their spouse caregivers
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Park S, Choi EK, Kim IR, Cho J, Jang JH
- KMID: 2451015
- Blood Res.
- 2019 Jun;54(2):137-143.
- doi: 10.5045/br.2019.54.2.137
BACKGROUND: Hematopoietic stem cell transplantation (HSCT) is an exhausting process that impacts both the patient and caregiver. METHODS: This was a cross-sectional, HSCT survivor-spouse caregiver matching study to determine quality of... -
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- Stem Cell-Based Therapies for Liver Diseases: An Overview and Update
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Wang J, Sun M, Liu W, Li Y, Li M
- KMID: 2449242
- Tissue Eng Regen Med.
- 2019 Apr;16(2):107-118.
- doi: 10.1007/s13770-019-00178-y
BACKGROUND: Liver disease is one of the top causes of death globally. Although liver transplantation is a very effective treatment strategy, the shortage of available donor organs, waiting list mortality,... -
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- The autophagy Protein Atg5 Plays a Crucial Role in the Maintenance and Reconstitution Ability of Hematopoietic Stem Cells
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Jung HE, Shim YR, Oh JE, Oh DS, Lee HK
- KMID: 2444160
- Immune Netw.
- 2019 Apr;19(2):e12.
- doi: 10.4110/in.2019.19.e12
Hematopoietic stem cells (HSCs) in bone marrow are pluripotent cells that can constitute the hematopoiesis system through self-renewal and differentiation into immune cells and red blood cells. To ensure a... -
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- Efficacy of parenteral glutamine supplementation in adult hematopoietic stem cell transplantation patients
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Cho YK, Hong SY, Jeon SJ, Namgung HW, Lee E, Lee E, Bang SM
- KMID: 2451052
- Blood Res.
- 2019 Mar;54(1):23-30.
- doi: 10.5045/br.2019.54.1.23
BACKGROUND: Hematopoietic stem cell transplantation (HSCT) patients need parenteral nutrition because of nausea, vomiting, and mucositis caused by conditioning regimens. The demand for glutamine increases during the HSCT period. We... -
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- Predictive Role of Circulating Immune Cell Subtypes Early after Allogeneic Hematopoietic Stem Cell Transplantation in Patients with Acute Leukemia
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Kim TW, Park SS, Lim JY, Min GJ, Park S, Jeon YW, Yahng SA, Shin SH, Lee SE, Yoon JH, Cho BS, Eom KS, Lee S, Kim HJ, Min CK
- KMID: 2447226
- Int J Stem Cells.
- 2019 Mar;12(1):73-83.
- doi: 10.15283/ijsc18094
BACKGROUND AND OBJECTIVES: Cells of innate immunity normally recover in the first weeks to months after allogenenic hematopoietic stem cell transplantation (allo-HSCT). Their relevance in terms of graft-versus-host disease (GVHD)... -
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- Perivascular Cells and NADPH Oxidase Inhibition Partially Restore Hyperglycemia-Induced Alterations in Hematopoietic Stem Cell and Myeloid-Derived Suppressor Cell Populations in the Bone Marrow
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Kim JY, Lee JY, Ha KS, Han ET, Park WS, Min CK, Hong SH
- KMID: 2447225
- Int J Stem Cells.
- 2019 Mar;12(1):63-72.
- doi: 10.15283/ijsc18097
BACKGROUND AND OBJECTIVES: Patients suffer from long-term diabetes can result in severe complications in multiple organs through induction of vascular dysfunctions. However, the effects of chronic hyperglycemic conditions on hematopoiesis... -
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- Generation of Organotypic Multicellular Spheres by Magnetic Levitation: Model for the Study of Human Hematopoietic Stem Cells Microenvironment
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MejÃa-Cruz CC, Barreto-Durán E, Pardo-Pérez MA, Jimenez MC, Rincón J, Vanegas K, RodrÃguez JL, Jaramillo-Garcia LF, Ulloa JC, DÃaz RM, Leal-GarcÃa E, Pérez-Núñez R, Barreto A, RodrÃguez-Pardo VM
- KMID: 2447224
- Int J Stem Cells.
- 2019 Mar;12(1):51-62.
- doi: 10.15283/ijsc18061
BACKGROUND AND OBJECTIVE: The characteristics of human hematopoietic stem cells are conditioned by the microenvironment of the bone marrow, where they interact with other cell populations, such as mesenchymal stem... -
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