J Korean Rheum Assoc.  2007 Dec;14(4):369-374.

Manifestations Like Multiple Sclerosis in a Paitent with Rheumatoid Arthritis and Sjogren's Syndrome

• Kim KM
• Jung HG
• Cho YS
• Chang JH
• Kim TW
• Lee CW

Abstract

Demyelinating syndrome can rarely occur in Sjogren's syndrome or rheumatoid arthritis. We describe a patient of Sjogren's syndrome with multiple sclerosis-like features whose rheumatoid arthritis has been managed for 3 years. The patient presented paraparesis and urinary retention, and improved with high-dose corticosteroid therapy.

Keyword

Sjogren's syndrome; Multiple sclerosis; Rheumatoid arthritis

MeSH Terms

Arthritis, Rheumatoid*
Humans
Multiple Sclerosis*
Paraparesis
Sjogren's Syndrome*
Urinary Retention

Figure

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  Fig. 1. FLAIR (A, B) and T2-weighted (C, D) brain MRI images show high signal lesions in the periventricular white matter and left thalamus.

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  Fig. 2. T2 weighted MRI image shows discontinuous high intensity signal from C5 to T9 levels of spinal cord.

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  Fig. 3. Multiple joint space narrow, ankylosis, and deformities of both hands are shown in the radiograph.

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  Fig. 4. Biopsy of labial salivary gland reveals focal infiltration of lymphocytes and plasma sells around the gland. Grade 4, focus score > 1 per 4 mm2 (H&E stain, x400).

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