Korean J Med.
2008 Jan;74(1):106-109.
Development of juvenile rheumatoid arthritis in a patient with multiple sclerosis
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- 1Department of Internal Medicine, Kyunghee University School of Medicine, Seoul, Korea. aprildaum@hanmail.net
Abstract
- Multiple sclerosis (MS) is an immune-mediated, inflammatory demyelinating disease of the central nervous system. The coexistence of multiple sclerosis and rheumatoid arthritis is very rare. This rare association is interesting due to the overlapping pathophysiological similarities of T-cells and tumor necrosis factor-alpha (TNF-alpha) in both diseases. We report a case of a Korean 10 year old girl with multiple sclerosis, who after 3 years developed a clinical and serological manifestation of juvenile rheumatoid arthritis.
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