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Clinical characteristics and survival of colorectal cancer patients in Korea stratified by age

Baek SK, Lee JS, Hwang IG, Kim JG, Kim TW, Sohn SK, Kang MY, Lee SC

Background/Aims: This nationwide study was undertaken to determine differences in clinicopathologic characteristics and survival of patients with colorectal cancer (CRC) according to age using big data from the Korean National...
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Single-nucleotide polymorphismbased epidemiological analysis of Korean Mycobacterium bovis isolates

Kim TW, Jang YH, Jeong MK, Seo Y, Park CH, Kang S, Lee YJ, Choi JS, Yoon SS, Kim JM

Background: Bovine tuberculosis (TB) is caused by Mycobacterium bovis, a well-known cause of zoonotic tuberculosis in cattle and deer, and has been investigated in many physiological and molecular studies. However,...
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Comparison of the Effectiveness of Three Lumbosacral Orthoses on Early Spine Surgery Patients: A Prospective Cohort Study

Jang SW, Yang HS, Kim YB, Yang JC, Kang KB, Kim TW, Park KH, Jeon KS, Shin HD, Kim YE, Cho HN, Lee YK, Lee Y, Lee SBN, Ahn DY, Sim WS, Jo M, Jo GJ, Park DB, Park GS

Objective To compare the convenience and effectiveness of the existing lumbosacral orthoses (LSO) (classic LSO and Cybertech) and a newly developed LSO (V-LSO) by analyzing postoperative data. Methods This prospective cohort...
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Parapapillary Intrachoroidal Cavitation in Glaucoma: Association with Choroidal Microvasculature Dropout

Kim J, Kim J, Lee EJ, Kim TW

Purpose: To characterize the choroidal microvasculature in glaucomatous eyes with parapapillary intrachoroidal cavitation (PICC) using optical coherence tomography angiography (OCTA) and its association with parapapillary choroidal microvasculature dropout (MvD). Methods: This...
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Genotypic characterization of fluoroquinolone-resistant Escherichia coli isolates from edible offal

Son SH, Seo KW, Kim YB, Noh EB, Lee KW, Oh TH, Kim SJ, Song JC, Kim TW, Lee YJ

Abstract: Edible offal is easily contaminated by Escherichia coli (E. coli) and fluoroquinolone (FQ)-resistant E. coli is considered a serious public health problem, thus, this study investigated the genetic characteristics...
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The hepato-protective effect of eupatilin on an alcoholic liver disease model of rats

Lee HY, Nam Y, Choi WS, Kim TW, Lee J, Sohn UD

Eupatilin is known to possess anti-apoptotic, anti-oxidative, and antiinflammatoryproperties. We report here that eupatilin has a protective effect onthe ethanol-induced injury in rats. Sprague–Dawley rats were divided into 6 groups:control,...
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Clinical Implication of Mid-Range Dynamic Instability in Lumbar Degenerative Spondylolisthesis

Lee CY, Park BM, Kim TW, Lee SH

Study Design: Retrospective evaluation. Purpose: To determine the prevalence of mid-range dynamic instability in patients with degenerative spondylolisthesis (DS) and to evaluate the clinical implication of mid-range instability (MI). Overview of Literature:...
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Construction reproducibility of a composite tooth model composed of an intraoral-scanned crown and a cone-beam computed tomography-scanned root

Lim SW, Moon RJ, Kim MS, Oh MH, Lee KM, Hwang HS, Kim TW, Baek SH, Cho JH

Objective: To evaluate the construction reproducibility of a composite tooth model (CTM) composed of an intraoral-scanned crown and a cone-beam computed tomography (CBCT)-scanned root. Methods: The study assessed 240 teeth...
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Treadmill Exercise Improves Motor Function and Short-term Memory by Enhancing Synaptic Plasticity and Neurogenesis in Photothrombotic Stroke Mice

Hong M, Kim M, Kim TW, Park SS, Kim MK, Park YH, Sung YH, Shin MS

Purpose: Thrombotic stroke is a type of ischemic stroke characterized by motor dysfunction and memory impairments. In the present study, the effect of treadmill exercise on motor function and short-term...
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Management of isolated para-aortic lymph node recurrence after surgery for colorectal cancer

Kim YI, Park IJ, Park JH, Kim TW, Ro JS, Lim SB, Yu CS, Kim JC

PURPOSE: The rare incidence of isolated para-aortic lymph node (PALN) recurrence of colorectal cancer has precluded the formulation of treatment guidelines. This study evaluated and compared the effects of different...
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Determinant of Quality of Life in Patients with Chronic Cerebral Infarct

Lee Y, Kim JS, Hong BY, Park JG, Yoo JW, Lee KB, Kim TW, Lim SH

This study investigated how physical and cognitive function and psychological factors affected the health-related quality of life (HRQoL, hereafter HQ) of stroke patients in South Korea. The study enrolled 32...
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Far Beyond Cancer Immunotherapy: Reversion of Multi-Malignant Phenotypes of Immunotherapeutic-Resistant Cancer by Targeting the NANOG Signaling Axis

Oh SJ, Lee J, Kim Y, Song KH, Cho E, Kim M, Jung H, Kim TW

Cancer immunotherapy, in the form of vaccination, adoptive cellular transfer, or immune checkpoint inhibitors, has emerged as a promising practice within the field of oncology. However, despite the developing field's...
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Clinical and Dermoscopic Features of Fungal Melanonychia: Differentiating from Subungual Melanoma

Kim HJ, Kim TW, Park SM, Lee HJ, Kim GW, Kim HS, Kim BS, Kim MB, Ko HC

Background Fungal melanonychia (FM) is a rare nail disorder that presents as dark pigmentation in the nail plate because of fungal nail infection. The diagnosis of FM is occasionally confusing because...
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Effectiveness of iron supplementation in the perioperative management of total knee arthroplasty: a systematic review

Lee SH, Kim JI, Choi W, Kim TW, Lee YS

Introduction/purpose: The purpose of this systematic review was to evaluate the effect of iron supplementation during total knee arthroplasty (TKA): (1) Is the iron supplementation necessary during TKA? (2) When...
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Does Hip Bone Density Differ between Paretic and Non-Paretic Sides in Hemiplegic Stroke Patients? and Its Relationship with Physical Impairment

Lee HY, Park JH, Lee H, Kim TW, Yoo SD

Background: Bone loss after stroke escalates the risk of fractures, mainly in the hip, leading to further disability in individuals with stroke. We aimed to investigate the skeletal effect of...
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Korean Clinical Practice Guideline for the Diagnosis and Treatment of Insomnia in Adults

Choi H, Youn S, Um YH, Kim TW, Ju G, Lee HJ, Lee C, Lee SD, Bae K, Kim SJ, Lee JH, Kim T, Chung S

Objective We aim to present a clinical guideline for the diagnosis and treatment of insomnia in adults by reviewing and integrating existing clinical guidelines. The purpose of this guideline is...
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Correlation between Sleep and C-reactive Protein of Patients in Amnestic Mild Cognitive Impairment and Alzheimer’s Dementia

Kim HY, Hong SC, Jeong JH, Seo HJ, Kim TW, Kim SM, Oh JH, Chung JS, Um YH

Objective: Sleep affects systemic inflammation and amyloid deposition, and sleep disturbance is known to be a risk factor for cognitive decline. To date, literatures on the relationship between peripheral inflammatory...
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Combined Delivery of Two Different Bioactive Factors Incorporated in Hydroxyapatite Microcarrier for Bone Regeneration

Kim TW, Ahn WB, Kim JM, Kim JH, Kim TH, Perez RA, Jang HS

BACKGROUND: The delivery of growth factors using a carrier system presents a promising and innovative tool in tissue engineering and dentistry today. Two of the foremost bioactive factors, bone morphogenetic...
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A Phase II Study of Avelumab Monotherapy in Patients with Mismatch Repair–Deficient/Microsatellite Instability–High or POLE-Mutated Metastatic or Unresectable Colorectal Cancer

Kim JH, Kim SY, Baek JY, Cha YJ, Ahn JB, Kim HS, Lee KW, Kim JW, Kim TY, Chang WJ, Park JO, Kim J, Kim JE, Hong YS, Kim YH, Kim TW

Purpose We evaluated the efficacy and safety of avelumab, an anti-PD-L1 antibody, in patients with metastatic or unresectable colorectal cancer (mCRC) with mismatch repair deficiency (dMMR)/microsatellite instability-high (MSI-H) or POLE mutations. Materials...
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Clinical Risk Factors for Complications in Patients Undergoing Percutaneous Transhepatic Cholangioscopy

Han SY, Kim TW, Kim DU, Park YJ, Lee MW, Kim S, Baek DH, Kim GH, Song GA

Background/Aim: Percutaneous transhepatic cholangioscopy (PTCS) has been widely used for the diagnosis and treatment. PTCS-related complications (hemobilia, cholangitis, biliary tract perforations) are not infrequent. However, data on the risk factors...
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