J Korean Med Sci.  2000 Feb;15(1):115-118. 10.3346/jkms.2000.15.1.115.

Primary Sjogren's syndrome manifested as multiple sclerosis and cutaneous erythematous lesions: a case report

• Jung SM
• Lee BG
• Joh GY
• Cha JK
• Chung WT
• Kim KH

• KMID: 1731247
• DOI: http://doi.org/10.3346/jkms.2000.15.1.115

Abstract

Sjogren's syndrome is a chronic autoimmune disorder characterized by lymphocytic infiltration of the lacrimal and salivary glands, leading to dryness of eyes (kerato-conjunctivitis sicca) and mouth (xerostomia). The skin lesions in Sjogren's syndrome are usually manifested as xeroderma, but sometimes appear as annular erythema or vasculitis. Central nervous system symptoms may be presented as one of extraglandular manifestations, though rare in incidence, and need differential diagnosis from multiple sclerosis. We report a case of a 45-year-old woman diagnosed as multiple sclerosis at first but later as neurologic manifestation of primary Sjogren's syndrome, showing signs of multiple sclerosis and cutaneous erythematous lesions.

Keyword

Sjogren's Syndrome; Multiple Sclerosis; Erythema

MeSH Terms

Case Report
Diagnosis, Differential
Erythema/pathology
Erythema/diagnosis*
Female
Human
Middle Age
Multiple Sclerosis/pathology
Multiple Sclerosis/diagnosis*
Sjogren's Syndrome/pathology
Sjogren's Syndrome/diagnosis*