J Korean Diet Assoc.  2002 May;8(2):199-205.

Development of anti-obesity dietary supplement decreasing nutrient absorption by digestive enzyme inhibition in gut

• Yoon Y
• Park Y
• Hong J
• Choi S
• Lee H
• Hong S

Abstract

In this study, we found a new food additive as an natural herbal extracts against lipid digestion enzymes for the regulation of fatty acid absorption and weight control. The Water extracts of Platycodon grandiflorum and Solanum melongena. inhibited lipase activity and decresed serum total cholesterol and triglyceride concentration in mouse fed lipid emulsion. Twenty three volunteers were subjected to the intake of the herbal extracts plus the egg yolk IgY that inhibit carbohydrate digestion enzymes in gut for 50 days. In average, the treated subjects appeared to lose 1.96 kg of body weight and 3.4 kg of body fat mass during the treated period. Furthermore, Panniculus adiposus and breech size were significantly decreased during the experimental period. Above results suggested that the administration of the dietary additives composed of natural herbal extract and egg yolk IgY improve the obesity by the decrement of body weight and body fat mass.

Keyword

Obesity; Natural herbal extracts; egg yolk IgY; Dietary additive

MeSH Terms

Absorption*
Adipose Tissue
Animals
Body Weight
Cholesterol
Dietary Supplements*
Digestion
Egg Yolk
Food Additives
Lipase
Mice
Obesity
Platycodon
Solanum melongena
Triglycerides
Volunteers
Water
Cholesterol
Food Additives
Lipase
Water