J Neurogastroenterol Motil.
2012 Apr;18(2):150-168.
Asian Consensus Report on Functional Dyspepsia
- Affiliations
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- 1Division of Upper Gastroenterology, Department of Internal Medicine, Hyogo College of Medicine, Hyogo, Japan.
- 2Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India.
- 3Department of Internal Medicine, Chulalongkorn University, Bangkok, Thailand.
- 4Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
- 5Department of Gastroenterology, Changi General Hospital, Singapore.
- 6Division of Gastroenterology, Taipei Veterans General Hospital, National Yang-Ming University School of Medicine, Taipei, Taiwan.
- 7Department of Comprehensive Medicine, Tohoku University Hospital, Sendai, Japan.
- 8Division of Gastroenterology, Union Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
- 9Siriraj Hospital, Mahidol University, Bangkok, Thailand.
- 10Department of Gastroenterology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
- 11Division of Gastroenterology, Kaoshiung Veterans General Hospital, National Yang-Ming University, Kaoshiung, Taiwan.
- 12Department of Gastroenterology, Ajou University School of Medicine, Suwon, Korea.
- 13Department of Medicine, University of Malaya, Kuala Lumpur, Malaysia.
- 14Department of Internal Medicine, National Defense Medical College, Saitama, Japan.
- 15Department of Gastroenterology, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.
- 16Department of Gastroenterology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
- 17Department of Internal Medicine, Jichi Medical University, Tochigi, Japan.
- 18Gastroenterology Unit, Department of Medicine, Thammasat University Hospital, Pathumthani, Thailand.
- 19Department of Medicine, University of Hong Kong, Hong Kong, China.
- 20Department of Gastroenterology, Korea University Guro Hospital, Seoul, Korea. drbakyt@korea.ac.kr
Abstract
- BACKGROUND/AIMS
Environmental factors such as food, lifestyle and prevalence of Helicobacter pylori infection are widely different in Asian countries compared to the West, and physiological functions and genetic factors of Asians may also be different from those of Westerners. Establishing an Asian consensus for functional dyspepsia is crucial in order to attract attention to such data from Asian countries, to articulate the experience and views of Asian experts, and to provide a relevant guide on management of functional dyspepsia for primary care physicians working in Asia.
METHODS
Consensus team members were selected from Asian experts and consensus development was carried out using a modified Delphi method. Consensus teams collected published papers on functional dyspepsia especially from Asia and developed candidate consensus statements based on the generated clinical questions. At the first face-to-face meeting, each statement was reviewed and e-mail voting was done twice. At the second face-to-face meeting, final voting on each statement was done using keypad voting system. A grade of evidence and a strength of recommendation were applied to each statement according to the method of the GRADE Working Group.
RESULTS
Twenty-nine consensus statements were finalized, including 7 for definition and diagnosis, 5 for epidemiology, 9 for pathophysiology and 8 for management. Algorithms for diagnosis and management of functional dyspepsia were added.
CONCLUSIONS
This consensus developed by Asian experts shows distinctive features of functional dyspepsia in Asia and will provide a guide to the diagnosis and management of functional dyspepsia for Asian primary care physicians.
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