- Association Between Body Mass Index and Functional Dyspepsia in Young Japanese People
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Yamamoto Y, Furukawa S, Watanabe J, Kato A, Kusumoto K, Takeshita E, Ikeda Y, Yamamoto N, Kohara K, Saeki Y, Hiasa Y
- KMID: 2528042
- J Neurogastroenterol Motil.
- 2022 Apr;28(2):276-282.
- doi: 10.5056/jnm21076
Background/Aims Evidence regarding the association between body mass index (BMI) and functional dyspepsia (FD) in the Asian population is limited. Further, no study has evaluated this issue in young people in Asian... -
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- Duodenal Microbiome and Its Clinical Implications in Functional Dyspepsia
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Kim SH
- KMID: 2527476
- Korean J Gastroenterol.
- 2022 Mar;79(3):91-98.
- doi: 10.4166/kjg.2022.027
Functional dyspepsia is one of the most common functional gastrointestinal disorders with chronic bothersome epigastric pain or postprandial fullness without a definite organic cause. Despite its high clinical burden, the... -
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- Autophagy and Digestive Disorders: Advances in Understanding and Therapeutic Approaches
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Thein W, Po WW, Choi WS, Sohn UD
- KMID: 2517153
- Biomol Ther.
- 2021 Jul;29(4):353-364.
- doi: 10.4062/biomolther.2021.086
The gastrointestinal (GI) tract is a series of hollow organs that is responsible for the digestion and absorption of ingested foods and the excretion of waste. Any changes in the... -
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- Motilitone toxicity in a dog
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Kim YH, Ahn JO, Jeong Y, Kang MS, Choi JH, Chung JY
- KMID: 2520053
- Korean J Vet Res.
- 2021 Jun;61(2):e15.
- doi: 10.14405/kjvr.2021.61.e15
A three-month-old, intact male Maltese dog was presented to the hospital with lethargy after taking human medication, Motilitone. Physical examination, including a neurological examination, revealed no remarkable findings, but cholinergic... -
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- Multicenter, Randomized, Placebo-controlled Trial to Evaluate the Efficacy and Safety of a Controlled-release, Once-daily UIC201609/UIC201610 Combination Therapy for Functional Dyspepsia: Preliminary Study
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Lee JW, Youn YH, Choi SC, Lee KJ, Kim N
- KMID: 2515138
- Korean J Gastroenterol.
- 2021 Apr;77(4):171-178.
- doi: 10.4166/kjg.2020.171
Background/Aims: Functional dyspepsia is a disease involving a range of upper gastrointestinal symptoms derived from various pathophysiologies. Tablets containing a combination of rabeprazole and controlled-release (CR) mosapride were recently developed. To... -
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- Efficacy and Safety of UI05MSP015CT in Functional Dyspepsia: A Randomized, Controlled Trial
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Yoon H, Lee DH, Lee YH, Jeong JC, Lee ST, Choi MG, Jeon SW, Shim KN, Baik GH, Kim JG, Moon JS, Sung IK, Lee SK, Rhee PL, Jung HY, Lee BE, Kim HS, Kim SG, Lee KM, Seong JK, Jang JS, Park JJ
- KMID: 2424079
- Gut Liver.
- 2018 Sep;12(5):516-522.
- doi: 10.5009/gnl17416
BACKGROUND/AIMS: To evaluate the efficacy and safety of a controlled release, once-daily formulation of mosapride (UI05MSP015CT) in patients with functional dyspepsia (FD). METHODS: Patients with FD were randomly assigned (1:1) to... -
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- Randomized, Double-blind, Placebo-controlled Clinical Trial for the Evaluation of the Efficacy and Safety of Artemisia and Green Tea Extract SD1003F in Volunteers with Helicobacter pylori-associated Gastric Discomfort
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Kwon SO, Kwak DY, Hong SP, Kim WH, Park JM, Han YM, Kang Y, Kang EA, Jo S, Hahm KB
- KMID: 2428898
- Korean J Helicobacter Up Gastrointest Res.
- 2018 Mar;18(1):38-49.
- doi: 10.7704/kjhugr.2018.18.1.38
BACKGROUND/AIMS: A previous study showed that dietary intervention with Artemisia and green tea extracts, i.e., SD1003F, relieved Helicobacter pylori-associated chronic atrophic gastritis in a mouse model. We continue the research... -
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- Is Helicobacter pylori Associated Functional Dyspepsia Correlated With Dysbiosis?
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Kim YJ, Chung WC, Kim BW, Kim SS, Kim JI, Kim NJ, Yoo J, Kim SH
- KMID: 2395418
- J Neurogastroenterol Motil.
- 2017 Oct;23(4):504-516.
- doi: 10.5056/jnm17066
BACKGROUND/AIMS: To assess the long-term effect of Helicobacter pylori eradication on symptomatic improvement according to the type of antibiotic and the duration of treatment in H. pylori-associated functional dyspepsia. METHODS: We... -
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- Understanding the Rome IV: Gastroduodenal Disorders
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Jung KW
- KMID: 2392343
- Korean J Med.
- 2017 Aug;92(4):362-365.
- doi: 10.3904/kjm.2017.92.4.362
Gastroduodenal symptoms are very common in the general population. The symptoms are classified into four categories according to the newly revised Rome IV criteria: functional dyspepsia (including postprandial discomfort and... -
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- Functional Dyspepsia: Advances in Diagnosis and Therapy
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Talley NJ
- KMID: 2412207
- Gut Liver.
- 2017 May;11(3):349-357.
- doi: 10.5009/gnl16055
Functional dyspepsia (FD) is a common but under-recognized syndrome comprising bothersome recurrent postprandial fullness, early satiety, or epigastric pain/burning. Epidemiologically, there are two clinically distinct FD syndromes (although these often... -
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- Current Status of Translational Research on Functional Dyspepsia
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Park JH, Kim JW, Park JK, Shin CM, Jung KW
- KMID: 2358714
- Korean J Gastroenterol.
- 2016 Sep;68(3):132-137.
- doi: 10.4166/kjg.2016.68.3.132
Functional dyspepsia (FD) has a diverse pathophysiology and treatment is difficult. Translational research to understand its pathophysiology is underway. Hormonal factors, including ghrelin, seem promising, offering an understanding of appetite... -
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- A Study of Effects of Psychosocial Factors and Quality of Life on Functional Dyspepsia in Firefighters
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Jang SH, Ryu HS, Choi SC, Lee HJ, Lee SY
- KMID: 2321478
- Korean J Psychosom Med.
- 2016 Jun;24(1):66-73.
- doi: 10.0000/kjpm.2016.24.1.66
OBJECTIVES: The purpose of this study was to investigate the characteristics of psychosocial factors related to functional dyspepsia(FD) and their effects on quality of life(QOL) in firefighters. METHODS: This study examined... -
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- Diagnosis and treatment of functional dyspepsia
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Shin CM, Huh KC
- KMID: 2161712
- J Korean Med Assoc.
- 2016 Apr;59(4):311-318.
- doi: 10.5124/jkma.2016.59.4.311
Functional dyspepsia is defined as the presence of the symptoms that originate from the gastroduodenal area, without evidence of any organic, systemic, or metabolic disease that could explain these symptoms.... -
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- Diet and Nutritional Management in Functional Gastrointestinal Disorder: Functional Dyspepsia
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Shin CM
- KMID: 2268864
- Korean J Med.
- 2016 Feb;90(2):98-104.
- doi: 10.3904/kjm.2016.90.2.98
Diet play an important role in triggering symptoms in patients with functional dyspepsia. The pathophysiology of functional dyspepsia is characterized by impaired gastric accommodation and visceral hypersensitivity, and patterns of... -
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- Randomized, Controlled, Multi-center Trial: Comparing the Safety and Efficacy of DA-9701 and Itopride Hydrochloride in Patients With Functional Dyspepsia
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Choi MG, Rhee PL, Park H, Lee OY, Lee KJ, Choi SC, Seol SY, Chun HJ, Rew JS, Lee DH, Song GA, Jung HY, Jeong HY, Sung IK, Lee JS, Lee ST, Kim SK, Shin YW
- KMID: 2433481
- J Neurogastroenterol Motil.
- 2015 Jul;21(3):414-422.
- doi: 10.5056/jnm14117
BACKGROUND/AIMS: Therapies of functional dyspepsia (FD) are limited. DA-9701 is a novel prokinetic agent formulated with Pharbitis semen and Corydalis Tuber. We aimed to assess the efficacy of DA-9701 compared... -
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- The Pharmacological Effects of Benachio-F(R) on Rat Gastrointestinal Functions
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Poudel BK, Yu JY, Kwon YS, Park HG, Son M, Jun JH, Kim JA, Kim JO
- KMID: 2382365
- Biomol Ther.
- 2015 Jul;23(4):350-356.
- doi: 10.4062/biomolther.2015.035
Functional dyspepsia (FD) is a prevalent idiopathic upper gastrointestinal (GI) disorder characterized by diverse symptomatology including epigastric pain or discomfort, postprandial fullness, and early satiety. Although its pathophysiological mechanisms have... -
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- Efficacy and Safety of New Prokinetic Agent Benachio Q Solution(R) in Patients with Postprandial Distress Syndrome Subtype in Functional Dyspepsia: A Single-center, Randomized, Double-blind, Placebo-controlled Pilot Study
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Shim YK, Lee JY, Kim N, Park YH, Yoon H, Shin CM, Park YS, Lee DH
- KMID: 2373307
- Korean J Gastroenterol.
- 2015 Jul;66(1):17-26.
- doi: 10.4166/kjg.2015.66.1.17
BACKGROUND/AIMS: Functional dyspepsia (FD) is a gastrointestinal disorder in which the patient suffers from chronic abdominal symptoms despite the absence of organic disease. Benachio Q solution (soln.)(R) is a new... -
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- Medical treatment of functional dyspepsia
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Kim SE
- KMID: 2308532
- Kosin Med J.
- 2015 Jun;30(1):1-11.
- doi: 10.7180/kmj.2015.30.1.1
Functional dyspepsia (FD) is a condition in which upper abdominal symptoms, such as epigastralgia, postprandial discomfort, and bloating, occur in the absence of any organic or metabolic disease that could... -
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- Impact of Eating Attitude and Impairment of Physical Quality of Life Between Tertiary Clinic and Primary Clinic Functional Dyspepsia Outpatients in Japan
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Shimpuku M, Futagami S, Tajima N, Yamawaki H, Maruki Y, Kodaka Y, Nagoya H, Gudis K, Kawagoe T, Sakamoto C
- KMID: 2381215
- J Neurogastroenterol Motil.
- 2014 Oct;20(4):506-515.
- doi: 10.5056/jnm14015
BACKGROUND/AIMS: There is no available data on factors associated with healthcare-seeking behavior for functional dyspepsia (FD) symptoms at either tertiary or primary clinics in Japan. Therefore, we aimed to compare... -
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- Effects of GC7101, a Novel Prokinetic Agent on Gastric Motor Function: Ex Vivo Study
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Jung DH, Choi EJ, Jeon HH, Lee YH, Park H
- KMID: 2381210
- J Neurogastroenterol Motil.
- 2014 Oct;20(4):469-474.
- doi: 10.5056/jnm14010
BACKGROUND/AIMS: GC7101, an extract of Lonicera Flos, is a novel developing drug for reflux esophagitis and functional dyspepsia. However, the drug's exact pharmacological mechanism of action remains unclear. This study... -
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