J Korean Soc Pediatr Nephrol.
2010 Apr;14(1):1-9.
Slowing the Progression of Chronic Kidney Disease in Children and Adolescents
- Affiliations
-
- 1Department of Pediatrics, Seoul National University Children's Hospital Kidney Institute, Seoul National University Medical Research Center, Seoul, Korea. ilsooha@snu.ac.kr
- 2Department of Pediatrics, Inje University Haeundae Paik Hospital, Korea.
Abstract
- Slowing the progression of chronic kidney disease is much more important in children and adolescents with a relatively longer remaining life span. A practical way to assess the rate of progression of chronic kidney disease is to measure the change of GFR estimated by formulae. To slow the progression, hypertension and proteinuria have to be controlled strictly, and hypoplastic anemia must be treated with erythropoietin. If not contraindicated, ACE inhibitor or angiotensin receptor blocker is recommended with monitoring of the side effects. Trials to slow the progression should be commenced as soon as the chronic kidney disease is confirmed and needs to be continued until renal transplantation as long as residual renal function remains. An online system, the Korean Pediatric Chronic Kidney Disease Registry (http://pedcrf.or.kr/), provides tools that are useful in evaluation and management of the children and adolescents with chronic kidney diseases.
