Child Kidney Dis.  2021 Jun;25(1):1-7. 10.3339/jkspn.2021.25.1.1.

Risk Factors for the Progression of Chronic Kidney Disease in Children

  • 1Department of Pediatrics, Seoul National University College of Medicine and Seoul National University Children’s Hospital; Kidney Research Institute, Medical Research Center, Seoul National University College of Medicine, Seoul, Republic of Korea


Chronic kidney disease (CKD) in children is associated with various complications, including poor growth and development, mineral bone disorder, cardiovascular disease, kidney failure, and mortality. Slowing down the progression of CKD is important since CKD is often not curable. Prospective cohort studies have been conducted to understand the progression and outcomes of CKD in children, and these studies have identified non-modifiable and modifiable risk factors. Recognition of known risk factors and early intervention are important to delay the progression of kidney function decline in children.


Chronic kidney disease; Risk factors; Children; Kidney failure
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