Tuberc Respir Dis.  2013 Feb;74(2):79-81.

A Fatal Case of Acute Respiratory Failure Caused by Mycobacterium massiliense

Affiliations
  • 1Division of Pulmonology, Department of Internal Medicine, Presbysterian Medical Center, Jeonju, Korea.
  • 2Department of Internal Medicine, Chonbuk National University Medical School, Jeonju, Korea. leeyc@jbnu.ac.kr
  • 3Research Center for Pulmonary Disorders, Chonbuk National University Medical School, Jeonju, Korea.
  • 4Research Institute of Clinical Medicine of Chonbuk National University-Biomedical Research Institute of Chonbuk National University Hospital, Jeonju, Korea.

Abstract

Few recent reports have indicated that Mycobacterium massiliense causes various infections including respiratory infection. However, there is scarce information on the clinical significance, natural history of the infection, and therapeutic strategy. This report describes a case of an immunocompetent old man infected by M. massiliense that causes acute respiratory failure. In light of the general courses of non-tuberculous mycobacterium infections, rapid progression and fatality are very rare and odd. In addition, we discuss the biological and pathological properties of M. massiliense with the review of cases reported previously including our fatal one.

Keyword

Mycobacterium; Mycobacterium Infections, Nontuberculous; Respiratory Insufficiency

MeSH Terms

Light
Mycobacterium
Mycobacterium Infections
Mycobacterium Infections, Nontuberculous
Natural History
Respiratory Insufficiency

Figure

  • Figure 1 (A) Chest X-ray showed increased opacities in the right lower lobe. (B, C) Contrast-enhanced computed tomography scan of chest demonstrated consolidation within air-bronchogram in the right lower lobe.

  • Figure 2 Chest X-ray during medical treatment in the intensive care unit showed diffuse bilateral infiltration.


Reference

1. Kim HY, Yun YJ, Park CG, Lee DH, Cho YK, Park BJ, et al. Outbreak of Mycobacterium massiliense infection associated with intramuscular injections. J Clin Microbiol. 2007. 45:3127–3130.
2. Kim HY, Kook Y, Yun YJ, Park CG, Lee NY, Shim TS, et al. Proportions of Mycobacterium massiliense and Mycobacterium bolletii strains among Korean Mycobacterium chelonae-Mycobacterium abscessus group isolates. J Clin Microbiol. 2008. 46:3384–3390.
3. Koh WJ, Jeon K, Lee NY, Kim BJ, Kook YH, Lee SH, et al. Clinical significance of differentiation of Mycobacterium massiliense from Mycobacterium abscessus. Am J Respir Crit Care Med. 2011. 183:405–410.
4. Griffith DE, Aksamit T, Brown-Elliott BA, Catanzaro A, Daley C, Gordin F, et al. An official ATS/IDSA statement: diagnosis, treatment, and prevention of nontuberculous mycobacterial diseases. Am J Respir Crit Care Med. 2007. 175:367–416.
5. Adekambi T, Reynaud-Gaubert M, Greub G, Gevaudan MJ, La Scola B, Raoult D, et al. Amoebal coculture of "Mycobacterium massiliense" sp. nov. from the sputum of a patient with hemoptoic pneumonia. J Clin Microbiol. 2004. 42:5493–5501.
6. Tortoli E, Gabini R, Galanti I, Mariottini A. Lethal Mycobacterium massiliense sepsis, Italy. Emerg Infect Dis. 2008. 14:984–985.
Full Text Links
  • TRD
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2024 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr