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The Association between Behavioral Risk Factors and Nontuberculous Mycobacterial Pulmonary Disease

Park Y, Kwak SH, Yong SH, Lee SH, Leem AY, Kim SY, Lee SH, Chung K, Kim EY, Jung JY, Park MS, Kim YS, Chang J, Kang YA

Purpose: We aimed to determine the relationship between environmental exposure and nontuberculous mycobacterial pulmonary disease (NTM-PD) in Korea. Materials and Methods: A group of 150 patients with NTM-PD and a control...
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Single-nucleotide polymorphismbased epidemiological analysis of Korean Mycobacterium bovis isolates

Kim TW, Jang YH, Jeong MK, Seo Y, Park CH, Kang S, Lee YJ, Choi JS, Yoon SS, Kim JM

Background: Bovine tuberculosis (TB) is caused by Mycobacterium bovis, a well-known cause of zoonotic tuberculosis in cattle and deer, and has been investigated in many physiological and molecular studies. However,...
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Continued Upward Trend in Non-Tuberculous Mycobacteria Isolation over 13 Years in a Tertiary Care Hospital in Korea

Ahn K, Kim YK, Hwang GY, Cho H, Uh Y

Purpose: Despite decreased prevalence of tuberculosis, the incidence of the diseases associated with nontuberculous mycobacteria (NTM) has been increasing in South Korea and around the world. The present retrospective study...
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Disseminated Mycobacterium Avium Complex in an Immunocompromised Patient

Lee WK, Shin JO, Kim HS, Ko HC, Kim MB, Kim BS

  • KMID: 2512421
  • Korean J Dermatol.
  • 2021 Jan;59(1):71-73.
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Treatment strategy for skin and soft tissue infections caused by nontuberculous mycobacteria following various procedures

Bae JY, Yun IS, Roh TS, Kim YS

Background The early diagnosis and treatment of skin and soft tissue infections caused by nontuberculous mycobacteria (NTM) are important, especially as infections with rapidly growing mycobacteria (RGM) are rare and...
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Diagnostic Potential of a PPE Protein Derived from Mycobacterium tuberculosis Beijing/K Strain

Kim A, Park KJ, Kim YS, Cho SN, Dockrell HM, Hur YG

Purpose: The prevalence of Mycobacterium tuberculosis (M. tb) and the status of M. bovis BCG vaccination may affect host immune responses to M.tb antigens. Understanding of the predominant local M....
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Clinical Study of Specific Cutaneous Complications after BCG Vaccination

Won SH, Shin K, Kim WI, Yang MY, Lee WK, Kim HS, Kim BS, Kim MB, Ko HC

  • KMID: 2505557
  • Korean J Dermatol.
  • 2020 Aug;58(7):453-458.
Background: Bacille Calmette-Guérin (BCG) vaccination has been widely used to prevent severe infections caused by Mycobacterium tuberculosis. Although BCG vaccination is generally safe, some cutaneous complications may occur. However, cutaneous...
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False-Positive Mycobacterium tuberculosis Detection: Ways to Prevent Cross- Contamination

Asgharzadeh M, Ozma MA, Rashedi J, Poor M, Agharzadeh V, Vegari A, Shokouhi B, Ganbarov K, Ghalehlou NN, Leylabadlo HE, Kafil HS

The gold standard method for diagnosis of tuberculosis is the isolation of Mycobacterium tuberculosis through culture, but there is a probability of cross-contamination in simultaneous cultures of samples causing false-positives....
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A rare case of bovine tuberculosis caused by Mycobacterium bovis in a domestic rabbit

Roh SG, Jang YH, Kim J, Lee K, So B, Choi EJ

A 12-month-old domestic rabbit died suddenly without specific clinical signs. Gross examination revealed irregular yellowish hepatic nodules with pus in the submandibular muscles, lungs, uterus, and small intestines. Histopathological examination...
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Evaluation of Diagnostic Performance of Three Real-Time PCR Assays for the Detection of Mycobacteria Species

Kim Sw, Park YH, Ko YJ, Kim YH, Kim CH, Lim CS

Background: The disease burden caused by Mycobacterium tuberculosis (MTB) complex continues to decrease in most countries. However, the diseases caused by the nontuberculous mycobacteria (NTM) become a public health problem....
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Evaluation of the AdvanSure TB/NTM Plus Real-Time PCR Assay for the Simultaneous Detection of Mycobacterium tuberculosis and Nontuberculous Mycobacteria from Clinical Specimens

Hahm C, So MK, Chung HS, Lee M

Background: The AdvanSure TB/NTM plus real-time PCR (AdvanSure plus PCR; LG Chem., Korea) assay has been developed to increase the diagnostic sensitivity of nontuberculous mycobacteria (NTM) compared with the currently...
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Frequency of Mycobacterium tuberculosis Among M. tuberculosis Complex Strains Isolated from Clinical Specimen

Cho H, Kim JB, Uh Y

BACKGROUND: Rapid and accurate detection of Mycobacterium tuberculosis (MTB) is of primary importance for infection control and selection of anti-tuberculosis drugs. However, most clinical laboratories report MTB complex (MTC) without...
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Treatment Outcomes after Discontinuation of Ethambutol due to Adverse Events in Mycobacterium avium Complex Lung Disease

Kwon YS, Kwon BS, Kim OH, Park YE, Shim TS, Chong YP, Jo KW

BACKGROUND: Long-term administration of ethambutol (EMB) for Mycobacterium avium complex lung disease (MAC-LD) sometimes leads to permanent discontinuation of EMB due to various adverse events. This study aimed to investigate...
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Diagnostic Performance of the GENEDIA MTB/NTM Detection Kit for Detecting Mycobacterium tuberculosis and Nontuberculous Mycobacteria With Sputum Specimens

Shin S, Yoo IY, Shim HJ, Kang OK, Jhun BW, Koh WJ, Huh HJ, Lee NY

The GENEDIA MTB/NTM Detection Kit (GENEDIA MTB/NTM; Green Cross Medical Science Corp., Chungbuk, Korea) is a multiplex real-time PCR assay used for differential identification of Mycobacterium tuberculosis complex (MTBC) and...
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Evaluation of the QuantaMatrix Multiplexed Assay Platform for Molecular Diagnosis of Multidrug- and Extensively Drug-Resistant Tuberculosis Using Clinical Strains Isolated in Myanmar

Chang Y, Kim S, Kim Y, Ei PW, Hwang D, Lee J, Chang CL, Lee H

BACKGROUND: Although the incidence of tuberculosis (TB) is decreasing, cases of multidrug-resistant (MDR) TB and extensively drug-resistant (XDR) TB continue to increase. As conventional phenotype drug susceptibility testing (pDST) takes...
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Delayed Nontuberculous Mycobacterium Manifestation 1 Year after a Dog Bite on the Hand

Song JK, Shin JH, Lee JY

Nontuberculous mycobacteria infection can show various clinical manifestations as over 190 different species of nontuberculous mycobacteria have been identified. Among them, skin and soft tissue infections are commonly related with...
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Recombinant Rv0753c Protein of Mycobacterium tuberculosis Induces Apoptosis Through Reactive Oxygen Species-JNK Pathway in Macrophages

Lee KI, Choi S, Choi HG, Kebede SG, Dang TB, Back YW, Park HS, Kim HJ

Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb), remains one of the most important infectious diseases worldwide. Mtb and its culture filtrates or sonic extracts induce apoptosis in macrophages. However, there...
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Effect of Photodynamic Therapy Enhanced by Methylene Blue on Drug-resistant Mycobacterium smegmatis

Jeong B, Kim JK, Bae T, Park I

Tuberculosis (TB) is an old disease caused by Mycobacterium tuberculosis. Although it has been known for humans for thousands of years, the treatment of this disease still requires a lengthy...
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Evaluating the Use of Distilled Water for Washing Sodium Hydroxide in Mycobacterial Culture

Baek HG, Ko HM, Lee MH

Background: Respiratory specimens subjected to mycobacterial detection were initially pretreated with N-acetyl-L-cysteine-sodium hydroxide (NALC-NaOH) to remove the mucus and normal flora. Next, they were washed and neutralized with phosphate-buffered solution...
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The Study of Association between Leprosy's Type and Apolipoprotein E Gene in Korean Persons Affected by Leprosy

Park JH, Kim YJ, Kim JP

Background: Apolipoprotein E protein is a family of apolipoproteins that play an important role in lipid metabolism. Apolipoprotein E genotype and single-nucleotide polymorphisms of genes are known to induce neurodegenerative...
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