Korean J Med.  2012 Aug;83(2):243-248.

Case of Mycobacterium Massiliense Infection Presenting as Recurrent Pneumonia in Sjogren's Syndrome

• Seo JY
• Lee BH
• Lee JW
• Lee MH
• O SG
• Cho HM
• Lee CW

Abstract

Mycobacterium massiliense is an emerging pathogen that is increasingly reported as a causative agent occurring during medical procedures, at surgical sites, and intramuscularly [1]. Although previously classified as part of M. abscessus, M. massiliense has recently been identified as a new species of rapidly growing nontuberculous mycobacteria [1,3] via a comparative sequence analysis of rpoB and hsp65 [3,5]. However, the clinical manifestations of M. massiliense have not been well characterized. We report here in a case of recurrent pneumonia for 3 years that improved with antibiotic treatment for M. massiliense in a 37-year-old woman with Sjogren's syndrome. The patient showed a substantial response to treatment with a combination of antimicrobial therapies comprising clarithromycin and amikacin without cefoxitin for 6 months. This is the first report of pulmonary infection of M. massiliense with Sjogren's syndrome in Korea.

Keyword

Nontuberculous mycobacteria; Mycobacterium massiliense; Pneumonia; Sjogren's syndrome

MeSH Terms

Adult
Amikacin
Cefoxitin
Clarithromycin
Female
Humans
Korea
Mycobacterium
Nontuberculous Mycobacteria
Pneumonia
Sequence Analysis
Sjogren's Syndrome
Amikacin
Cefoxitin
Clarithromycin