Tuberc Respir Dis.  2006 Jul;61(1):26-33.

Application of Noninvasive Positive Pressure Ventilation in Patients with Respiratory Failure

• Seol YM
• Park YE
• Kim SR
• Lee JH
• Lee SJ
• Kim KU
• Cho JH
• Park HK
• Kim YS
• Lee MK
• Park SK
• Kim YD

Abstract

BACKGROUND: Noninvasive positive pressure ventilation(NPPV) has been increasingly used over the past decade in the management of acute or chronic respiratory failure and weaning of mechanical ventilation. We performed this clinical study to evaluate the usefulness of NPPV in patients who developed acute respiratory failure or post-extubation respiratory failure.
METHODS
We analysed thirty four patients(sixteen males and eighteen females, mean ages 58 years) who applied NPPV(BIPAP S/T, Respironics co., USA) for respiratory failure or weaning difficulty at medical intensive care unit(MICU), emergency room and general ward of a tertiary hospital. We evaluated the underlying causes of respiratory failure, duration of treatment, the degree of adaptation, complication and predictive parameters of successful outcome.
RESULTS
The overall success rate of NPPV was seventy-one percent. The duration of NPPV applying time, baseline blood pressure, pulse rate, respiration rate, PaO2, PaCO2, SaO2 were not different between success group and failure group. But, the baseline pH was higher in the success group. Predictors of success were higher baseline pH, patients with underlying disease of COPD, improvement of vital sign and arterial blood gas value after NPPV application. The success rate in patients with post-extubation respiratory failure was eighty percent. There were no serious complication on applying NPPV except minor complications such as facial skin erythema, abdominal distension & dry mouth.
CONCLUSION
NPPV may be effective treatment in patients with acute respiratory failure or post-extubation respiratory failure in selected cases.

Keyword

Positive pressure ventilation; Intubation; COPD

MeSH Terms

Blood Pressure
Emergency Service, Hospital
Erythema
Female
Heart Rate
Humans
Hydrogen-Ion Concentration
Critical Care
Intubation
Male
Mouth
Patients' Rooms
Positive-Pressure Respiration*
Pulmonary Disease, Chronic Obstructive
Respiration, Artificial
Respiratory Insufficiency*
Respiratory Rate
Skin
Tertiary Care Centers
Vital Signs
Weaning

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