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Implications of Managing Chronic Obstructive Pulmonary Disease in Cardiovascular Diseases

Deshmukh K, Khanna A

Globally, cardiovascular diseases and chronic obstructive pulmonary disease (COPD) are the leading causes of the noncommunicable disease burden. Overlapping symptoms such as breathing difficulty and fatigue, with a lack of...
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Association of sarcopenia with osteoporosis in patients with chronic obstructive pulmonary disease

Chua JR, Tee ML

Objectives: Systemic consequence of Chronic Obstructive Pulmonary Disease (COPD) is associated with progressive loss of muscle mass and function. Preliminary studies showed presence of sarcopenia in COPD leads to reduced...
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Current Situation of Home Oxygen Therapy for Chronic Obstructive Pulmonary Disease Patients in Korea

Kim JK, Jang SH, Park S, Kim JH, Park JY, Yoo KH, Kim YS, Lim SY, Hwang YI

BACKGROUND: Long-term oxygen therapy provides various benefits, including prolonged survival for severely hypoxic chronic obstructive pulmonary disease (COPD) patients. However, adequate management strategies for home oxygen therapy are not well...
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Clinical Phenotypes, Comorbidities, and Exacerbations according to Serum 25-OH Vitamin D and Plasma Fibrinogen Levels in Chronic Obstructive Pulmonary Disease

Hyun DG, Oh YM, Lee SW, Lee SD, Lee JS

BACKGROUND: Although vitamin D deficiency is prevalent in patients with chronic obstructive pulmonary disease (COPD), the influence of vitamin D deficiency on COPD has not been fully established. Moreover, the...
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Effect of Pyunkang-tang on Inflammatory Aspects of Chronic Obstructive Pulmonary Disease in a Rat Model

Seo HS, Lee HJ, Lee CJ

We investigated the anti-inflammatory effect of Pyunkang-tang extract (PGT), a complex herbal extract based on traditional Chinese medicine that is used in Korea for controlling diverse pulmonary diseases, on cigarette...
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COPD as a Disease of Immunosenescence

Cho WK, Lee CG, Kim LK

Although chronic obstructive pulmonary disease (COPD) is regarded as a chronic inflammatory lung disease, the disease mechanism is still not known. Intriguingly, aging lungs are quite similar to COPD-affected lungs...
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Effects of Aging and Smoking Duration on Cigarette Smoke-Induced COPD Severity

Kim EJ, Yoon SJ, Kim YE, Go DS, Jung Y

BACKGROUND: Aging can serve as an underlying mechanism of chronic obstructive pulmonary disease (COPD). Also, smoking, which is the most common cause of COPD, is responsible for the systemic manifestations...
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Effect of Depression on Pulmonary Symptoms and Quality of Life in Patients with Chronic Obstructive Pulmonary Disease

Kim D, Han S, Jung SS, Kim JO, Lee SW

OBJECTIVES: Depression is a common comorbid condition in patients with chronic obstructive pulmonary disease (COPD) and has a higher prevalence than the general population. On the other hand, studies on...
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Impact of the Endothelial Tight Junction Protein Claudin-5 on Clinical Profiles of Patients With COPD

Kim BG, Lee PH, Lee SH, Baek AR, Park JS, Lee J, Park SW, Kim DJ, Park CS, Jang AS

PURPOSE: The tight junction protein claudin-5 (CLDN5) is critical to the control of endothelial cellular polarity and pericellular permeability. The role of CLDN5 in chronic obstructive pulmonary disease (COPD) remains...
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The Effect of Neuromuscular Electrical Stimulation on Pulmonary Function, Gait Ability, and Quality of Life in Patients with Chronic Obstructive Pulmonary Disease

Kang JI, Park JS, Jeong DK

PURPOSE: This study aims to investigate the changes in pulmonary function, gait ability, and quality of life when NMES is applied along with CBE and to provide basic clinical data...
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Establishment of a chronic obstructive pulmonary disease mouse model based on the elapsed time after LPS intranasal instillation

Lee SY, Cho JH, Cho SS, Bae CS, Kim GY, Park DH

Chronic obstructive pulmonary disease (COPD) was the 3rd leading cause of death in 2012 worldwide. It is particularly severe in the elderly, who are at risk of death by coughing,...
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Significance of Low-Attenuation Cluster Analysis on Quantitative CT in the Evaluation of Chronic Obstructive Pulmonary Disease

Nambu A, Zach J, Kim SS, Jin G, Schroeder , Kim YI, Bowler R, Lynch DA

OBJECTIVE: To assess clinical feasibility of low-attenuation cluster analysis in evaluation of chronic obstructive pulmonary disease (COPD). MATERIALS AND METHODS: Subjects were 199 current and former cigarette smokers that underwent CT...
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Association between Genetic Variations of MERTK and Chronic Obstructive Pulmonary Disease in Koreans

Kim WJ, Park HJ, Choi YJ, Kwon EY, Kim BM, Lee JH, Chang JH, Lee Kang J, Choi JH

BACKGROUND: Chronic obstructive pulmonary disease (COPD) is a debilitating lung disease. To date, a large number of clinical studies have been conducted to investigate the association between genetic variations and...
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Symptom Experience, Self-Efficacy, Depression, and Medication Adherence in Patients with Chronic Obstructive Pulmonary Disease

Park S, Kang Y

PURPOSE: This study was done to investigate the correlation among symptom experience, self-efficacy, depression, and medication adherence in patients with chronic obstructive pulmonary disease (COPD). METHODS: Participants were 100 patients with...
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Therapeutic Potential of Medicinal Plants and Their Constituents on Lung Inflammatory Disorders

Kim HP, Lim H, Kwon YS

Acute bronchitis and chronic obstructive pulmonary diseases (COPD) are essentially lung inflammatory disorders. Various plant extracts and their constituents showed therapeutic effects on several animal models of lung inflammation. These...
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The Airflow Obstruction and Subjective Health Status Among Stable Chronic Obstructive Pulmonary Disease Patients Residing in the Community

Song HY

PURPOSE: This study was undertaken to examine the relationship between airflow obstruction and subjective health status reported by stable patients with chronic obstructive pulmonary disease (COPD) residing in the community. METHODS:...
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A Sleepy Man with Chronic Obstructive Pulmonary Disease-Obstructive Sleep Apnea Overlap Syndrome

Ji KH

Chronic obstructive pulmonary disease (COPD) and obstructive sleep apnea (OSA) are prevalent and commonly co-occur as overlap syndrome. Patients with an overlap syndrome have a worse prognosis than those with...
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Nutrient intake and dietary quality of Korean adults according to chronic obstructive pulmonary disease (COPD): Based on the 2012~2014 Korea National Health and Nutrition Examination Survey

Kang BM, Park HR, Lee YM, Song KH

PURPOSE: Food intake of COPD patients decreases because of appetite loss, depression, and breathing problems while eating, which increase the likelihood of patients becoming malnourished. This study investigated the nutrient...
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IgG Sensitization to Extracellular Vesicles in Indoor Dust Is Closely Associated With the Prevalence of Non-Eosinophilic Asthma, COPD, and Lung Cancer

Kim YS, Choi JP, Kim MH, Park HK, Yang S, Kim YS, Kim TB, Cho YS, Oh YM, Jee YK, Lee SD, Kim YK

PURPOSE: Recent experimental evidence shows that extracellular vesicles (EVs) in indoor dust induce neurtrophilic pulmonary inflammation, which is a characteristic pathology in patients with severe asthma and chronic obstructive pulmonary...
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Chronic obstructive pulmonary disease (COPD) assessment test scores corresponding to modified Medical Research Council grades among COPD patients

Lee CH, Lee J, Park YS, Lee SM, Yim JJ, Kim YW, Han SK, Yoo CG

BACKGROUND/AIMS: In assigning patients with chronic obstructive pulmonary disease (COPD) to subgroups according to the updated guidelines of the Global Initiative for Chronic Obstructive Lung Disease, discrepancies have been noted...
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